Results 131 to 140 of about 181,465 (294)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A Multi-coloured survey of NGC 253 with XMM-Newton

open access: yes, 2007
There is a large body of work that has used the excellent Chandra observations of nearby galaxies with neglible low mass X-ray binary (LMXB) populations. This has culminated in a ``Universal'' X-ray luminosity function (XLF) for high mass X-ray binaries (
Barnard, R., Greening, L. Shaw, Kolb, U.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Patogenicidade de Beauveria bassiana ao psilídeo Diaphorina citri e compatibilidade do fungo com produtos fitossanitários Beauveria bassiana pathogenicity to Diaphorina citri and compatibility of the fungus with phytosanitary products

open access: yesPesquisa Agropecuária Brasileira, 2012
O objetivo deste trabalho foi avaliar a patogenicidade de Beauveria bassiana a ninfas de Diaphorina citri (Hemiptera: Psyllidae) e verificar a compatibilidade do fungo com produtos fitossanitários e sua persistência em plantas de citros.
Ana Paula Ferreira Pinto   +3 more
doaj  

Greening Bonnaroo: exploring the rhetoric and reality of a sustainable festival through micro-ethnographic methods [PDF]

open access: yes, 2010
This research revealed that the greening policies of the Bonnaroo Festival are translated into sustainable event practice through: educational activities for volunteers and festival-goers, the creation of spaces of hyper-sustainability within the event ...
Kennell, James, Sitz, Rebekah
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Flowering, forcing, storage and vase life of Hamamelis

open access: yesEuropean Journal of Horticultural Science, 2009
A. Sæbø, S. O. Grimstad
doaj   +1 more source

USING PLANTS FOR GREENING OF TAILING PONDS OF IRON ORE COMBINES OF KRYVYI RIH AREA [PDF]

open access: yes, 2018
The tailing ponds of the iron ore-dressing combines occupy thousands of hectares in Kryvyi Rih area and create a serious ecologic problem in this region.
Baranets, Mykola   +8 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Impact of a new nucleo-cytoplasmic composition on the citrus fuit quality : [23] [PDF]

open access: yes, 2008
Organic acids, sugars and carotenoids are implied in the fruit quality. A cybrid has been obtained by symmetric protoplast fusion between Willow leaf mandarin (Citrus deliciosa Ten.) and Eureka lemon (Citrus limon (L.) Buno.).
Bassene, Jean Baptiste   +7 more
core  

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