Results 71 to 80 of about 24,531 (312)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Walkability and Greenness Do Not Walk Together: Investigating Associations between Greenness and Walkability in a Large Metropolitan City Context

open access: yes, 2021
Background: The existing environment literature separately emphasizes the importance of neighborhood walkability and greenness in enhancing health and wellbeing. Thus, a desirable neighborhood should ideally be green and walkable at the same time.
Faysal Kabir Shuvo   +8 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Residential greenness and birth outcomes: evidence for reduced low birth weight from an umbrella review and harmonized normalized difference vegetation index synthesis

open access: yesFrontiers in Public Health
IntroductionResidential green space is increasingly recognized as a potential protective factor for maternal and neonatal health, yet the evidence regarding its association with low birth weight (LBW) and preterm birth (PTB) remains inconsistent ...
Lisa Bauleo   +4 more
doaj   +1 more source

Critical windows of greenness exposure during preconception and gestational periods in association with birthweight outcomes

open access: yesEnvironmental Research: Health, 2023
Few studies have examined the association between greenness exposure and birth outcomes. This study aims to identify critical exposure time windows during preconception and pregnancy for the association between greenness exposure and birth weight.
Zhenchun Yang   +16 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Global greenness in relation to reducing the burden of cardiovascular diseases: ischemic heart disease and stroke

open access: yesEnvironmental Research Letters, 2020
This ecological study aimed to identify the association between greenness and cardiovascular diseases in terms of ischemic heart disease (IHD) and stroke in 183 countries worldwide. The country-level disability-adjusted life year (DALY) database provided
Aji Kusumaning Asri   +7 more
doaj   +1 more source

Association Between Long‐Term Exposure to Fine Particulate Matter Constituents and Progression of Cerebral Blood Flow Velocity in Beijing: Modifying Effect of Greenness

open access: yesGeoHealth, 2023
Few studies have explored the effects of fine particulate matter (PM2.5) and its constituents on the progression of cerebral blood flow velocity (BFV) and the potential modifying role of greenness.
Zongkai Xu   +11 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Greenness assessment of supply chains via intuitionistic fuzzy based approaches

open access: yes, 2021
The increase in the consumption level of products with various materials has resulted in many problems. A worrisome result of this situation is environmental problems. Thus, environmental considerations during the planning, designing, implementation, and
TUZKAYA, GÜLFEM   +1 more
core   +1 more source

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