Results 51 to 60 of about 16,319 (268)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Stay-Green Not Always Stays Green [PDF]

Molecular Plant, 2014
Senescence is a highly regulated recycling process in which nutrients are translocated from deteriorating leaves to newly developing leaves, flowers, seeds, or roots (Lim et al., 2007; Gregersen et al., 2013). Chloroplast dismantling, a major event during senescence, involves the degradation of light-harvesting chlorophyll a/b-binding proteins (LHCPs ...
openaire   +3 more sources

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

A Comprehensive Assessment of Sample Preparation Methods for the Determination of UV Filters in Water by Gas Chromatography–Mass Spectrometry: Greenness, Blueness, and Whiteness Quantification Using the AGREEprep, BAGI, and RGB 12 Tools

Applied Sciences
Sample preparation is a key step in the analytical procedure. This step is a time- and labor-consuming process, and often it is also expensive, with costs being influenced by the consumption of materials and reagents.
Grażyna Wejnerowska, Izabela Narloch
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Global greenness in relation to reducing the burden of cardiovascular diseases: ischemic heart disease and stroke

Environmental Research Letters, 2020
This ecological study aimed to identify the association between greenness and cardiovascular diseases in terms of ischemic heart disease (IHD) and stroke in 183 countries worldwide. The country-level disability-adjusted life year (DALY) database provided
Aji Kusumaning Asri, Chia-Pin Yu, Wen-Chi Pan, Yue Leon Guo, Huey-Jen Su, Shih-Chun Candice Lung, Chih-Da Wu, John D Spengler   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Validation, measurement uncertainty estimation and evaluation of UHPLC greenness for simultaneous determination of metoprolol tartrate and hydrochlorothiazide in binary tablet

Journal of Taibah University for Science
A novel green ultra high performance liquid chromatography (UHPLC) method was validated and estimated the measurement uncertainty for simultaneous determination of metoprolol tartrate (MET) and hydrochlorothiazide (HCT) in binary tablet. A Zorbax® SB-C18
Claudia Vilela de Oliveira, Adriano Peron, Anas Rashid, Frank Alonso Gavilano Fajardo, Felipe Rebello Lourenço, Marina Franco Maggi Tavares, María Segunda Aurora Prado   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

GResilience: Decision-Making Policies for Trading Off Greenness and Resilience in Online Collaborative AI Systems

IEEE Access
Problem: An Online Collaborative AI System (OL-CAIS) learns online from human collaboration to achieve a common goal. It may be subjected to environmental events that disrupt the system’s decision-making policies, resulting in performance ...
Diaeddin Rimawi, Antonio Liotta, Marco Todescato, Barbara Russo   +3 more
doaj   +1 more source