Results 41 to 50 of about 24,531 (312)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Association between Urban Greenness and Depressive Symptoms: Evaluation of Greenness Using Various Indicators

, 2019
An increasing number of studies have suggested benefits of greenness exposure on mental health. We examined the association between urban greenness and depressive symptoms in adults in the general population living in the seven major cities in Korea (N =
Yongsoo Choi, Hyomi Kim, Kevin James Lane, Minh Le, Jong-Tae Lee, Hyeonjin Song, Honghyok Kim, Garam Byun, Chan Ryul Park   +8 more
core   +1 more source

Greenness and Depression Incidence among Older Women [PDF]

, 2019
BACKGROUND: Recent evidence suggests that higher levels of residential greenness may contribute to better mental health. Despite this, few studies have considered its impact on depression, and most are cross-sectional.
Banay, Rachel, John D. Spengler, Jaime E. Hart, Olivia I. Okereke, James, Peter, Kubzansky, Laura, Spengler, John, Hart, Jaime, Laura D. Kubzansky, Francine Laden, Donna Spiegelman, Rachel F. Banay, Peter James, Okereke, Olivia, Spiegelman, Donna, Laden, Francine   +15 more
core   +1 more source

Impact of afforestation policy on vegetation greenness in China

, 2022
Understanding the spatiotemporal change of greenness and the main driving factors affecting greenness can provide an effective theoretical basis for ecological environment protection and restoration in China.
Xie, Wentong, Hamm, Nicholas, Ge, Yong, Foody, Giles   +3 more
core   +1 more source

Start of the Green Season and Normalized Difference Vegetation Index in Alaska’s Arctic National Parks

Remote Sensing, 2021
Daily Normalized Difference Vegetation Index (NDVI) values from the MODIS Aqua and Terra satellites were compared with on-the-ground camera observations at five locations in northern Alaska.
David K. Swanson
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An Ultra-Fast Validated Green UPLC-MS/MS Approach for Assessing Revumenib in Human Liver Microsomes: In Vitro Absorption, Distribution, Metabolism, and Excretion and Metabolic Stability Evaluation

Medicina
Background and Objectives: Revumenib (SNDX-5613) is a powerful and specific inhibitor of the menin–KMT2A binding interaction. It is a small molecule that is currently being researched to treat KMT2A-rearranged (KMT2Ar) acute leukemias.
Mohamed W. Attwa, Ali S. Abdelhameed, Adnan A. Kadi   +2 more
doaj   +1 more source

Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening

Pharmaceutics, 2023
Alectinib, also known as Alecensa®, is prescribed for the therapeutic treatment of individuals diagnosed with metastatic non-small cell lung cancer (NSCLC) who have a specific genetic mutation referred to as anaplastic lymphoma kinase (ALK) positivity ...
Mohamed W. Attwa, Haitham AlRabiah, Gamal A. E. Mostafa, Adnan A. Kadi   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Residential Greenness and Birthweight in the State of Massachusetts, USA [PDF]

, 2018
Natural vegetation, or greenness, may benefit maternal health and consequently, fetal growth, by providing opportunities for physical activity and psychological restoration, and decreasing detrimental environmental exposures.
Schwartz, Joel, Petros Koutrakis, Coull, Brent, Koutrakis, Petros, James, Peter, Kloog, Itai, Joel Schwartz, Kelvin Fong, Fong, Kelvin, Francine Laden, Brent Coull, Kelvin C. Fong, Brent A. Coull, Itai Kloog, Peter James, Laden, Francine, Joel D. Schwartz   +16 more
core   +1 more source