Results 61 to 70 of about 1,076,377 (343)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Using Text Mining to Search for Neolithic Vlaardingen Culture Sites in the Rhine-Meuse-Scheldt Delta

open access: yesJournal of Computer Applications in Archaeology
This paper presents a study on Vlaardingen Culture (3400–2500 BCE) sites in the Rhine-Meuse-Scheldt delta using AGNES, an intelligent search engine for Dutch and Flemish archaeological grey literature. The aims of this paper are twofold: 1) to provide an
Lasse Van den Dikkenberg, Alex Brandsen
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

How low can you go? Towards a hierarchy of grey literature. [PDF]

open access: yes, 2008
In recent times health sciences librarians have become increasingly involved in working closely with researchers who are undertaking literature reviews (often, but not always, systematic literature reviews).
Tyndall, Jessica
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Almost half of references in reports on new and emerging nondrug health technologies are grey literature

open access: yesJournal of the Medical Library Association, 2019
Objective: The research investigated how frequently grey literature is used in reports on new and emerging nondrug health technologies, which sources are most cited, and how grey literature searching is reported.
Kelly Farrah, Monika Mierzwinski-Urban
doaj   +1 more source

On the effects of high-order scattering in 3D cubical and rectangular furnaces [PDF]

open access: yes, 2008
The discrete ordinates method (DOM/Sn) is implemented to investigate the high order scattering effects of absorbing–emitting–scattering grey gas media inside the three-dimensional cubical and rectangular furnaces.
Paul, M.C.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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