Results 41 to 50 of about 68,028 (256)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
New Bathonian (Middle Jurassic) sauropod remains from the Valtos Formation, Isle of Skye, Scotland [PDF]
, 2016 The discovery of a sauropod tooth and a single sauropod footprint from the Valtos Formation supplements our knowledge of these dinosaurs from the Middle Jurassic of the Isle of Skye.
Clark, Neil D.L., Gavin, Patrick
core +4 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Exploiting Environmental Computation in a Multi-Agent Model of Slime Mould
, 2015 Very simple organisms, such as the single-celled amoeboid slime mould Physarum polycephalum possess no neural tissue yet, despite this, are known to exhibit complex biological and computational behaviour.
Jones, Jeff
core +1 more source
Analysis of optical density wave propagation and cell movement in the cellular slime mould Dictyostelium discoideum [PDF]
, 1991 We have studied optical density wave propagation during aggregation of the cellular slime mould Dictyostelium discoideum in a quantitative manner by digital image analysis.
Siegert, Florian, Weijer, Cornelis J.
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Development of disease control strategies for organically grown field vegetables (DOVE) (OF0168) [PDF]
, 2002 This is the final report of Defra project OF0168 (DOVE). The attached main report starts with a more detailed and comprehensive Executive Summary, from which this text has been extracted.
Gladders, Dr Peter
core
Slime mould tactile sensor [PDF]
, 2013 Slime mould P. polycephalum is a single cells visible by unaided eye. The cells shows a wide spectrum of intelligent behaviour. By interpreting the behaviour in terms of computation one can make a slime mould based computing device.
Adamatzky, Andrew
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source