Results 41 to 50 of about 15,164,145 (290)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Grid-Forming: A Control Approach to Go Further Offshore?

Electricity
Offshore wind farms are increasingly being commissioned farther from shore, and high voltage alternating current (HVAC) transmission systems are preferred because of their maturity and reliability.
Rui Alves, Thyge Knuppel, Agustí Egea-Àlvarez   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Dynamic Interaction and Stability Analysis of Grid-following Converter Integrated Into Weak Grid

CSEE Journal of Power and Energy Systems
The grid-connected converter with grid-following control (GCC-GFL) for renewable energy sources has a risk of instability when integrated into the weak grid. This paper aims to investigate the dynamic interactions and stability characteristics of the GCC-
Shuang Li, Haijiao Wang, Yuehui Huang, Guoqing He, Chun Liu, Weisheng Wang   +5 more
doaj   +1 more source

Hybrid Voltage-Current Control of Grid-Forming and Grid-Following Inverters

CoRR
Grid-connected inverters are required to operate stably under a wide range of grid conditions. However, conventional grid-following (GFL) control may suffer from instability under weak-grid conditions, while grid-forming (GFM) control may exhibit unstable oscillations under strong-grid conditions.
Zirui Wang, Yitong Li, Quanchi Wu, Jinjun Liu   +3 more
openaire   +3 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Coordinated control between a grid forming inverter and grid following inverters suppling power in a standalone microgrid

Global Energy Interconnection, 2022
Battery energy storage systems, fuel cells, and photovoltaic generators are being adopted in distribution networks to achieve CO2 emission reduction. These power sources require inverters to connect to AC networks.
Junichi Araia, Yasuhiro Taguchi
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Grid-Forming Voltage-Source Inverter for Hybrid Wind-Solar Systems Interfacing Weak Grids

IEEE Open Journal of Power Electronics
This paper presents a grid-forming (GFM) voltage-source inverter (VSI) with direct current regulation for a hybrid wind-solar generator, enabling stable operation at very weak grid conditions and under faults.
Amr Radwan, Mahmoud A. Elshenawy, Yasser Abdel-Rady I. Mohamed, Ehab Fahmy El-Saadany   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source