Toroidal topology of population activity in grid cells [PDF]
Nature, 2022 The medial entorhinal cortex is part of a neural system for mapping the position of an individual within a physical environment1. Grid cells, a key component of this system, fire in a characteristic hexagonal pattern of locations2, and are organized in ...
Richard J Gardner +2 more
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Grid cells, border cells, and discrete complex analysis [PDF]
Frontiers in Computational Neuroscience, 2023 We propose a mechanism enabling the appearance of border cells—neurons firing at the boundaries of the navigated enclosures. The approach is based on the recent discovery of discrete complex analysis on a triangular lattice, which allows constructing ...
Yuri Dabaghian
doaj +6 more sources
During hippocampal inactivation, grid cells maintain synchrony, even when the grid pattern is lost [PDF]
eLife, 2019 The grid cell network in the medial entorhinal cortex (MEC) has been subject to thorough testing and analysis, and many theories for their formation have been suggested.
Noam Almog +5 more
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Grid cells in rats deprived of geometric experience during development. [PDF]
Proc Natl Acad Sci U S A, 2023 Significance An animal’s current position is encoded by specialized neurons in the medial entorhinal cortex, including grid cells and head direction cells. The location and direction-coding properties of these cells can be observed at early postnatal age
Ulsaker-Janke I +4 more
europepmc +2 more sources
Optogenetic pacing of medial septum parvalbumin-positive cells disrupts temporal but not spatial firing in grid cells. [PDF]
Sci Adv, 2021 Spatial code of grid cells is independent of theta oscillations and phase precession. Grid cells in the medial entorhinal cortex (MEC) exhibit remarkable spatial activity patterns with spikes coordinated by theta oscillations driven by the medial septal ...
Lepperød ME +6 more
europepmc +2 more sources
Orientation Invariant Sensorimotor Object Recognition Using Cortical Grid Cells [PDF]
Frontiers in Neural Circuits, 2022 Grid cells enable efficient modeling of locations and movement through path integration. Recent work suggests that the brain might use similar mechanisms to learn the structure of objects and environments through sensorimotor processing.
Kalvyn Roux +2 more
doaj +2 more sources
Grid cells are modulated by local head direction. [PDF]
Nat Commun, 2020 Grid and head direction codes represent cognitive spaces for navigation and memory. Pure grid cells generate grid codes that have been assumed to be independent of head direction, whereas conjunctive cells generate grid representations that are tuned to ...
Gerlei K +6 more
europepmc +2 more sources
Efficient and flexible representation of higher-dimensional cognitive variables with grid cells. [PDF]
PLoS Comput Biol, 2020 We shed light on the potential of entorhinal grid cells to efficiently encode variables of dimension greater than two, while remaining faithful to empirical data on their low-dimensional structure. Our model constructs representations of high-dimensional
Klukas M, Lewis M, Fiete I.
europepmc +2 more sources
A memory model of rodent spatial navigation in which place cells are memories arranged in a grid and grid cells are non-spatial [PDF]
eLifeA theory and neurocomputational model are presented that explain grid cell responses as the byproduct of equally dissimilar hippocampal memories. On this account, place and grid cells are best understood as the natural consequence of memory encoding and ...
David E Huber
doaj +2 more sources
A Framework for Intelligence and Cortical Function Based on Grid Cells in the Neocortex. [PDF]
Front Neural Circuits, 2018 How the neocortex works is a mystery. In this paper we propose a novel framework for understanding its function. Grid cells are neurons in the entorhinal cortex that represent the location of an animal in its environment.
Hawkins J +4 more
europepmc +2 more sources