Results 41 to 50 of about 756,985 (253)
Probabilistic Learning by Rodent Grid Cells. [PDF]
PLoS Comput Biol, 2016 Mounting evidence shows mammalian brains are probabilistic computers, but the specific cells involved remain elusive. Parallel research suggests that grid cells of the mammalian hippocampal formation are fundamental to spatial cognition but their diverse response properties still defy explanation.
Cheung A.
europepmc +9 more sources
On the optimality of grid cells
CoRR, 2016 Grid cells, discovered more than a decade ago [5], are neurons in the brain of mammals that fire when the animal is located near certain specific points in its familiar terrain. Intriguingly, these points form, for a single cell, a two-dimensional triangular grid, not unlike our Figure 3.
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GABAA Receptor Subunit α3 in Network Dynamics in the Medial Entorhinal Cortex
Frontiers in Systems Neuroscience, 2019 Layer II of the medial entorhinal cortex (MEC LII) contains the largest number of spatially modulated grid cells and is one of the first regions in the brain to express Alzheimer’s disease (AD)-related pathology.
Nina Berggaard +2 more
doaj +1 more source
To be a Grid Cell: Shuffling procedures for determining “Gridness” [PDF]
, 2017 Abstract Grid cells in freely behaving mammals are defined by the strikingly regular periodic spatial distribution of their firing. The standard method of identification calculates the “Gridness” of the spatial firing pattern, with significance being defined relative to the 95 th ...
Barry, C., Burgess, N.
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Functional properties of stellate cells in medial entorhinal cortex layer II
eLife, 2018 Layer II of the medial entorhinal cortex (MEC) contains two principal cell types: pyramidal cells and stellate cells. Accumulating evidence suggests that these two cell types have distinct molecular profiles, physiological properties, and connectivity ...
David C Rowland +6 more
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Modeling Grid Cell Distortions with a Grid Cell Calibration Mechanism
Cyborg and Bionic SystemsThe medial entorhinal cortex of rodents is known to contain grid cells that exhibit precise periodic firing patterns based on the animal’s position, resulting in a distinct hexagonal pattern in space. These cells have been extensively studied due to their potential to unveil the navigational computations that occur within the mammalian brain and ...
Daniel Strauß +4 more
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A new direction for grid cells [PDF]
Learning & Behavior, 2015 Krupic, Bauza, Burton, Barry, & O'Keefe (Grid cell symmetry is shaped by environmental geometry. Nature, 518, 232-235, 2015) found that the grids of grid cells in the entorhinal cortex of rats become sparser at the sharp end of a trapezoidal space. This makes grids, and grid cells, unsuitable for measuring distance traveled (odometry) and suggests that
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Evaluating State Space Discovery by Persistent Cohomology in the Spatial Representation System
Frontiers in Computational Neuroscience, 2021 Persistent cohomology is a powerful technique for discovering topological structure in data. Strategies for its use in neuroscience are still undergoing development.
Louis Kang +3 more
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