Results 51 to 60 of about 756,985 (253)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

A model combining oscillations and attractor dynamics for generation of grid cell firing

Frontiers in Neural Circuits, 2012
Different models have been able to account for different features of the data on grid cell firing properties, including the relationship of grid cells to cellular properties and network oscillations. This paper describes a model that combines elements of
Michael E Hasselmo, Mark P. Brandon
doaj   +1 more source

Unique grid cell identification of Croatian official map grids [PDF]

Journal of Maps, 2014
The Unique Grid Cell Identification (UGCI) system was created using the Croatian cartographic map grid system as a basis for development. A short description of the Croatian map grid system is therefore provided. Cartographic map nomenclature is used to uniquely identify map sheets; e.g. grid cells.
Duplančić Leder, Tea, Župan, Robert, Hećimović, Željko   +2 more
openaire   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Continuous attractor dynamics in spatial navigation: from population geometry to flexible computation

Frontiers in Neuroscience
A central computational problem in spatial navigation is how spatial representations remain stable under noise and uncertainty, and update reliable estimations of continuous variables such as head-direction and position, which respectively rely on the ...
Yani Chen, Yani Chen, Mu Hua, Xuelong Sun, Xuelong Sun, Jigen Peng, Jigen Peng   +6 more
doaj   +1 more source

Biomimetic SLAM Algorithm Based on Growing Self-Organizing Map

IEEE Access, 2021
A Biomimetic SLAM Algorithm Based on Growing Self-Organizing Map (GSOM-BSLAM), inspired by spatial cognitive mechanism of mammalian hippocampus, is proposed to resolve uncertainty problems in location identification and lack of real-time performance in ...
Yukun Zhang, Mengyuan Chen, Dehong Tian, Lingmei Ding   +3 more
doaj   +1 more source

Modeling grid fields instead of modeling grid cells [PDF]

, 2018
A neuron’s firing correlates are defined as the features of the external world to which its activity is correlated. In many parts of the brain, neurons have quite simple such firing correlates. A striking example are grid cells in the rodent medial entorhinal cortex: their activity correlates with the animal’s position in space, defining ‘grid fields ...
Sophie Rosay, Simon Weber 0004, Marcello Mulas   +2 more
openaire   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories

eLife
Spatial periodicity in grid cell firing has been interpreted as a neural metric for space providing animals with a coordinate system in navigating physical and mental spaces.
Rebecca RG, Giorgio A Ascoli, Nate M Sutton, Holger Dannenberg   +3 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source