Results 1 to 10 of about 22,347 (143)

Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1 [PDF]

open access: yeseLife, 2022
Standard models for spatial and episodic memory suggest that the lateral entorhinal cortex (LEC) and medial entorhinal cortex (MEC) send parallel independent inputs to the hippocampus, each carrying different types of information.
Brianna Vandrey   +4 more
doaj   +3 more sources

Entorhinal cortex and parahippocampus volume reductions impact olfactory decline in aged subjects

open access: yesBrain and Behavior, 2021
Introduction Pathological abnormalities first appear in the medial temporal regions including entorhinal cortex and parahippocampus in patients with Alzheimer's disease.
Natsuko Iizuka   +13 more
doaj   +1 more source

Crossed Entorhino-Dentate Projections Form and Terminate With Correct Layer-Specificity in Organotypic Slice Cultures of the Mouse Hippocampus

open access: yesFrontiers in Neuroanatomy, 2021
The entorhino-dentate projection, i.e., the perforant pathway, terminates in a highly ordered and laminated fashion in the rodent dentate gyrus (DG): fibers arising from the medial entorhinal cortex (MEC) terminate in the middle molecular layer, whereas ...
Lars Hildebrandt-Einfeldt   +10 more
doaj   +1 more source

Medial entorhinal cortex lesions induce degradation of CA1 place cell firing stability when self-motion information is used

open access: yesBrain and Neuroscience Advances, 2020
The entorhinal–hippocampus network plays a central role in navigation and episodic memory formation. To investigate these interactions, we examined the effect of medial entorhinal cortex lesions on hippocampal place cell activity.
Pierre-Yves Jacob   +4 more
doaj   +1 more source

Early memory deficits and extensive brain network disorganization in the AppNL-F/MAPT double knock-in mouse model of familial Alzheimer’s disease

open access: yesAging Brain, 2022
A critical challenge in current research on Alzheimer’s disease (AD) is to clarify the relationship between network dysfunction and the emergence of subtle memory deficits in itspreclinical stage.
Christopher Borcuk   +11 more
doaj   +1 more source

Medial temporal lobe and obstructive sleep apnea: Effect of sex, age, cognitive status and free-water

open access: yesNeuroImage: Clinical, 2022
Medial temporal structures, namely the hippocampus, the entorhinal cortex and the parahippocampal gyrus, are particularly vulnerable to Alzheimer’s disease and hypoxemia. Here, we tested the associations between obstructive sleep apnea (OSA) severity and
Marie-Ève Martineau-Dussault   +21 more
doaj   +1 more source

Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands

open access: yesNature Communications, 2022
Extensive studies concluded that homophilic interactions between pre- and postsynaptic teneurins, evolutionarily conserved cell-adhesion molecules, encode the specificity of synaptic connections.
Xuchen Zhang   +3 more
doaj   +1 more source

Effects of acetylcholine on neuronal properties in entorhinal cortex

open access: yesFrontiers in Behavioral Neuroscience, 2012
The entorhinal cortex receives prominent cholinergic innervation from the medial septum and the vertical limb of the diagonal band of Broca (MSDB). To understand how cholinergic neurotransmission can modulate behavior, research has been directed towards ...
James G Heys   +4 more
doaj   +1 more source

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