Results 1 to 10 of about 22,462 (202)

Entorhinal cortex and parahippocampus volume reductions impact olfactory decline in aged subjects

Brain and Behavior, 2021
Introduction Pathological abnormalities first appear in the medial temporal regions including entorhinal cortex and parahippocampus in patients with Alzheimer's disease.
Natsuko Iizuka, Yuri Masaoka, Satomi Kubota, Haruko Sugiyama, Masaki Yoshida, Akira Yoshikawa, Nobuyoshi Koiwa, Motoyasu Honma, Keiko Watanabe, Shotaro Kamijo, Sawa Kamimura, Masahiro Ida, Kenjiro Ono, Masahiko Izumizaki   +13 more
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Crossed Entorhino-Dentate Projections Form and Terminate With Correct Layer-Specificity in Organotypic Slice Cultures of the Mouse Hippocampus

Frontiers in Neuroanatomy, 2021
The entorhino-dentate projection, i.e., the perforant pathway, terminates in a highly ordered and laminated fashion in the rodent dentate gyrus (DG): fibers arising from the medial entorhinal cortex (MEC) terminate in the middle molecular layer, whereas ...
Lars Hildebrandt-Einfeldt, Kenrick Yap, Mandy H. Paul, Carolin Stoffer, Nadine Zahn, Alexander Drakew, Maximilian Lenz, Andreas Vlachos, Andreas Vlachos, Andreas Vlachos, Thomas Deller   +10 more
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Medial entorhinal cortex lesions induce degradation of CA1 place cell firing stability when self-motion information is used

Brain and Neuroscience Advances, 2020
The entorhinal–hippocampus network plays a central role in navigation and episodic memory formation. To investigate these interactions, we examined the effect of medial entorhinal cortex lesions on hippocampal place cell activity.
Pierre-Yves Jacob, Tiffany Van Cauter, Bruno Poucet, Francesca Sargolini, Etienne Save   +4 more
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Early memory deficits and extensive brain network disorganization in the AppNL-F/MAPT double knock-in mouse model of familial Alzheimer’s disease

Aging Brain, 2022
A critical challenge in current research on Alzheimer’s disease (AD) is to clarify the relationship between network dysfunction and the emergence of subtle memory deficits in itspreclinical stage.
Christopher Borcuk, Céline Héraud, Karine Herbeaux, Margot Diringer, Élodie Panzer, Jil Scuto, Shoko Hashimoto, Takaomi C. Saido, Takashi Saito, Romain Goutagny, Demian Battaglia, Chantal Mathis   +11 more
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Medial temporal lobe and obstructive sleep apnea: Effect of sex, age, cognitive status and free-water

NeuroImage: Clinical, 2022
Medial temporal structures, namely the hippocampus, the entorhinal cortex and the parahippocampal gyrus, are particularly vulnerable to Alzheimer’s disease and hypoxemia. Here, we tested the associations between obstructive sleep apnea (OSA) severity and
Marie-Ève Martineau-Dussault, Claire André, Véronique Daneault, Andrée-Ann Baril, Katia Gagnon, Hélène Blais, Dominique Petit, Jacques Y. Montplaisir, Dominique Lorrain, Célyne Bastien, Carol Hudon, Maxime Descoteaux, Arnaud Boré, Guillaume Theaud, Cynthia Thompson, Julie Legault, Guillermo E. Martinez Villar, Alexandre Lafrenière, Chantal Lafond, Danielle Gilbert, Julie Carrier, Nadia Gosselin   +21 more
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Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands

Nature Communications, 2022
Extensive studies concluded that homophilic interactions between pre- and postsynaptic teneurins, evolutionarily conserved cell-adhesion molecules, encode the specificity of synaptic connections.
Xuchen Zhang, Pei-Yi Lin, Kif Liakath-Ali, Thomas C. Südhof   +3 more
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Effects of acetylcholine on neuronal properties in entorhinal cortex

Frontiers in Behavioral Neuroscience, 2012
The entorhinal cortex receives prominent cholinergic innervation from the medial septum and the vertical limb of the diagonal band of Broca (MSDB). To understand how cholinergic neurotransmission can modulate behavior, research has been directed towards ...
James G Heys, Nathan W Schultheiss, Christopher F Shay, Yusuke eTsuno, Michael E Hasselmo   +4 more
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Relaxin-3 Innervation From the Nucleus Incertus to the Parahippocampal Cortex of the Rat

Frontiers in Neuroanatomy, 2021
Spatial learning and memory processes depend on anatomical and functional interactions between the hippocampus and the entorhinal cortex. A key neurophysiological component of these processes is hippocampal theta rhythm, which can be driven from ...
Cristina García-Díaz, Isis Gil-Miravet, Hector Albert-Gasco, Hector Albert-Gasco, Aroa Mañas-Ojeda, Francisco Ros-Bernal, Esther Castillo-Gómez, Esther Castillo-Gómez, Andrew L. Gundlach, Francisco E. Olucha-Bordonau, Francisco E. Olucha-Bordonau   +10 more
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Combinatorial expression of Lef1, Lhx2, Lhx5, Lhx9, Lmo3, Lmo4, and Prox1 helps to identify comparable subdivisions in the developing hippocampal formation of mouse and chicken

Frontiers in Neuroanatomy, 2014
We carried out a study of the expression patterns of seven developmental regulatory genes (Lef1, Lhx2, Lhx9, Lhx5, Lmo3, Lmo4, and Prox1), in combination with topological position, to identify the medial pallial derivatives, define its major subdivisions,
Antonio eAbellán, Ester eDesfilis, Loreta eMedina   +2 more
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Intrinsic Projections of Layer Vb Neurons to Layers Va, III, and II in the Lateral and Medial Entorhinal Cortex of the Rat

Cell Reports, 2018
Summary: Layer V of the entorhinal cortex (EC) receives input from the hippocampus and originates main entorhinal outputs. The deep-sublayer Vb, immunopositive for the transcription factor Ctip2, is thought to be the main recipient of hippocampal ...
Shinya Ohara, Mariko Onodera, Øyvind W. Simonsen, Rintaro Yoshino, Hiroyuki Hioki, Toshio Iijima, Ken-Ichiro Tsutsui, Menno P. Witter   +7 more
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