Si-Yuan Sun +4 more
semanticscholar +1 more source
Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy
A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu +15 more
wiley +1 more source
Experimental Study on Grinding for Hole-Making of 2.5D C/SiC Composites Using Diamond Core Drills. [PDF]
Chen B +6 more
europepmc +1 more source
The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi +11 more
wiley +1 more source
Investigation of Surface Integrity in Ultra-Precision Grinding of TiC-Reinforced Ti<sub>3</sub>SiC<sub>2</sub> (MAX Phase Composite). [PDF]
Wilhelm DP +4 more
europepmc +1 more source
A novel B2‐ordered Ti‐Zr‐V‐Al medium‐entropy intermetallic is developed through controlled metastability engineering, which activates an ordered TRIP effect via a new B2→D019‐α2 transformation with a distinctive {0001}α2//{110}B2, <11‐20>α2//<100>B2 orientation relationship. This alloy achieves an elongation of ∼7%, a strength of ∼1.1 GPa, and superior
Chaohua Li +8 more
wiley +1 more source
Influence of Grinding Process Parameters on the Three-Dimensional Surface Roughness of Silicon Carbide Particle-Reinforced Aluminum Matrix (SiCp/Al) Composites. [PDF]
Li Z, Wang S, Zhao Y, Zhang L, Deng Z.
europepmc +1 more source
A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li +12 more
wiley +1 more source
Integration of the D‐genome reshapes gene transcription, chromatin architecture, and the metabolome of hexaploid wheat, leading to enhanced adaptability to salt, UV‐B, and alkali stress. ABSTRACT The hybridization‐led integration of the D‐genome into domesticated tetraploid wheat gave rise to allohexaploid wheat, the most cultivated wheat globally ...
Yanyan Liu +23 more
wiley +1 more source
Neuromuscular Responses of the Cranio-Cervico-Mandibular System During Professional "110th Targa Florio" Rally Competitions: An Electromyographic Study in Real-World Racing Conditions. [PDF]
Fontana DA +9 more
europepmc +1 more source

