Results 171 to 180 of about 12,982,827 (271)

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang   +10 more
wiley   +1 more source

Decoupling Stable Cyclic Deformation From Defect Accumulation in Metals

open access: yesAdvanced Science, EarlyView.
Introducing amorphous nanoparticles into a metal matrix enables a cyclic deformation regime where strain hardening and defect accumulation are decoupled. These nanoparticles act as dislocation sinks and undergo reversible shear transformations, sustaining microstructural stability over millions of cycles.
Chenjun Ye   +9 more
wiley   +1 more source

Gut Microbiota‐Derived Indole‐3‐Acetaldehyde Contributes to the Disease‐Alleviating Effects of Kurarinone in Experimental Autoimmune Encephalomyelitis

open access: yesAdvanced Science, EarlyView.
Kurarinone ameliorates EAE via the gut microbiota‐indole‐3‐acetaldehyde‐AhR axis. Kurarinone reshapes gut microbiota and increases Akkermansia muciniphila, which promotes intestinal indole‐3‐acetaldehyde production. Indole‐3‐acetaldehyde crosses the intestinal barrier, activates AhR in CD4+ T cells, upregulates SOCS1/3, inhibits JAK2 and STAT3/4 ...
Xinyan Han   +11 more
wiley   +1 more source

Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang   +6 more
wiley   +1 more source

Decoupling Chemical and Mechanical Contributions to Capacity Fading in Ni‐Rich Cathodes for Sulfide‐Based All‐Solid‐State Batteries

open access: yesAdvanced Energy Materials, EarlyView.
Ni‐rich cathodes in sulfide‐based ASSBs undergo intertwined (electro)chemical and mechanical degradation. Here, a new diagnostic framework is presented to decouple each contribution by partitioning capacity fading into charge and discharge fading.
Jangwhan Seok   +12 more
wiley   +1 more source

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