Results 141 to 150 of about 43,630 (259)

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Microstructure and Properties of CBN Abrasive Blocks with Cu-Sn-Ti Binder Modified by Ceramic Glass Powder. [PDF]

Materials (Basel)
Zhang H, Duan D, Cao C, Li C, Zheng S.
europepmc   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Experimental Study on Grinding for Hole-Making of 2.5D C/SiC Composites Using Diamond Core Drills. [PDF]

Materials (Basel)
Chen B, Liu X, Sun S, Liu R, Quan W, Yi J, Guo Y.   +6 more
europepmc   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Bond Strength of Injectable Composites Under Different Enamel Treatments and Bonding Strategies. [PDF]

Clin Exp Dent Res
Chaves JDP, Camargo ES, Rached RN, de Souza EM.   +3 more
europepmc   +1 more source

A Superstrong and Ultratough Stretchable Electronic Conductor With Ultradurable Strain‐Insensitive Electromechanical Performance

Advanced Science, EarlyView.
We report a superstrong, ultratough, and fatigue‐resistant stretchable electronic conductor (SEC) integrating a viscoplastic quasi‐solid LM‐Ag alloy with a supramolecular elastomer. Unlike conventional LM, the alloy exhibits thixotropic flow, reduced surface tension, and enhanced interfacial interactions with the elastomer.
Yuxing Shan, Dong Lei, Chengzhi Huang, Chunhong Gong, Jingwei Zhang, Xiaokong Liu   +5 more
wiley   +1 more source

Grinding Metamorphic Layer of Bearing Steel: Formation Mechanisms, Characterization, and Process Parameter Effects. [PDF]

Materials (Basel)
Guo J, Xia T, Cao D, Liu X, Zhang W, Liu Y, Zhu J.   +6 more
europepmc   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

Advanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu, Shanyao Liu, Haixin Liang, Jiani Yang, Yanhe Li, Jiqing Yin, Xueguang Zhang, Yan Zhang, Dandan Bai, Zihui Yan, Zhuoao Zhang, Yanping Jia, Kuisheng Liu, Yifan Sheng, Jiani Xiang, Chenxiang Xi, Baoxing Dong, Xinyi Lei, Jiayu Chen, Hong Wang, Yi Guo, Yanping Zhang, Shaorong Gao, Wenqiang Liu   +23 more
wiley   +1 more source

Prediction of the surface roughness of Ti-6Al-4 V alloy during surface grinding using machine learning models. [PDF]

Sci Rep
Siri Varsha Reddy K, Adithi B, Nirupashree R, Hari Lokitha S, Satish Kumar T, Ghadai RK, Kalita K.   +6 more
europepmc   +1 more source