Results 71 to 80 of about 20,859 (257)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Development of gripping devices
, 2006 78 p.In order to meet the requirement of the developed science and technology, a special type of gripping device that is powerful and small in size has to be developed.
Tan, Shi Hui.
core
Modernization of the load gripping device for forestry industry
, 2023 The article proposes to install toothed plates on the contact surfaces of a foreign-made friction-clamping load-gripping device. The modernization of the friction-clamping load-gripping device is designed to use the device when moving goods from wood ...
A. N. Korolevskikh +2 more
core +1 more source
Danish Journal of ArchaeologyThis article examines the role of Scandinavian animal styles in the early Viking Age. It first assesses several strands of relevant discourse in the research history. One line of argument suggests a link between early and late animal styles.
Mats Skare
doaj +1 more source
The Taplow drinking horn: gripping-arm gestures and female performance in the migration period
, 2018 In the past two decades human representational art in migration-period Scandinavia and early Anglo-Saxon England has been recognised as an important research topic, illuminating novel ways to explore performance and enactment (e.g.
Brundle, L.
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Hexacopter with gripping module
, 2018 The 2018 CPS-VO challenge is a competition focusing on the development of a drone which has the ability to search a area for a lost drone and recover it to a specific destination, all this is to be done autonomous.
Andersson, Emil, Bogga, Anders
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source