Results 101 to 110 of about 176,683 (297)

Alternative Grit Models: Explorations Into the Psychometric Properties of Grit-S and Academic Performance

open access: yesInternational Journal of Educational Psychology
Grit, the passion for achieving long-term goals, has been conceived as a two-dimensional construct (Consistency of interest and Perseverance of effort). The construct is well known for its easy measurement and its relationship with performance, including
Miguel Eduardo Uribe-Moreno   +3 more
doaj   +1 more source

Independent measurement of the top quark mass and the light- and bottom-jet energy scales at hadron colliders [PDF]

open access: yes, 2007
A method for the simultaneous determination of the energy scales for b-quark jets and light jets, the jet energy resolution, and the top quark mass at hadron colliders is presented.
A. Abulencia   +8 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Grit is associated with lower level of depression and anxiety among university students in Chiang Mai, Thailand: A cross-sectional study.

open access: yesPLoS ONE, 2018
BACKGROUND:Depression and anxiety symptoms are prevalent among university students in both developed and developing settings. Recently, grit, defined as perseverance and passion for long-term goals, has emerged as an indicator of success and well-being ...
Patou Masika Musumari   +6 more
doaj   +1 more source

Do NEETs Need Grit? [PDF]

open access: yes, 2014
This paper investigates the relationship between personality traits in adolescence and education and labour market choices. In particular, we investigate the impact of grit (a tendency and ability to sustain interest in long term goals - perseverance) on
Ian Walker, Silvia Mendolia
core   +1 more source

Grit [PDF]

open access: yesFamily Medicine, 2021
Emily Mofield, Megan Parker Peters
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Institutional Childcare: An Overview on the German Market [PDF]

open access: yes
Institutional early childhood education and care can be funded and delivered in various ways relying on both the public and the private sector. The provision of childcare ranges from public operation to mixed markets with public and private providers to ...
Muehler, Grit
core  

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