Modeling Functional Connectivity for Bears Among Spawning Salmon Waterways in Haíɫzaqv (Heiltsuk) Territory, Coastal British Columbia. [PDF]
Mihalik I +5 more
europepmc +1 more source
Beyond the Edge: Basal‐Plane Defects as the Dominant Catalytic Sites in Sulfur‐Doped Graphene
Identification of basal‐plane sites in sulfur‐doped graphene challenges the conventional edge‐focused catalytic picture. Sulfur dopants together with inevitable oxygen‐containing groups modulate local charge and spin distributions, enhancing lithium binding and activating ORR/NRR intermediates.
Xuanhao Yuan +5 more
wiley +1 more source
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv +12 more
wiley +1 more source
Energy homeostasis regulatory peptides in hibernating grizzly bears. [PDF]
Gardi J +5 more
europepmc +1 more source
A residual‐charge‐induced electric field control (SDREC) strategy enables the fabrication of patterned microstructure arrays with a resolution of 20 µm via the selective deposition of charged droplets. The resulting arrays exhibit reversible writing/erasing, optical encryption, and selective silver electrode formation, offering a versatile route to ...
Yuechen Pei +8 more
wiley +1 more source
One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy
This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu +8 more
wiley +1 more source
Coexisting With Humans: Genomic and Behavioral Consequences in a Small and Isolated Bear Population. [PDF]
Fabbri G +20 more
europepmc +1 more source
Diet and environment shape fecal bacterial microbiota composition and enteric pathogen load of grizzly bears. [PDF]
Schwab C +4 more
europepmc +1 more source
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
Forecasting Root Rot Disease through Predictive Microbial Functional Profiling
Predicting soil‐borne disease moves beyond observation with a framework that elevates microbial functional genes into reliable forecasting biomarkers. By coupling targeted qPCR assays for core stress‐response genes with machine learning, this method detects root rot risks in pre‐symptomatic soils with over 80% accuracy.
Chuan You +11 more
wiley +1 more source

