Results 141 to 150 of about 35,246 (224)

Rewiring β₂-adrenergic receptor signaling: harnessing non-canonical GRK functions to treat metabolic diseases. [PDF]

Signal Transduct Target Ther
Cullum SA, Bock A.
europepmc   +1 more source

Little Scientists & Social Apprentices: Active Word Learning in Dynamic Social Contexts Using a Transparent Dyadic Interaction Platform

Social Development, Volume 35, Issue 1, February 2026.
ABSTRACT Research characterises the child as an active learner who attends more to and selectively retains information they actively elicit better than information they passively receive. At the same time, children learn best from knowledgeable others who tailor information to children's learning progress.
Ricarda Bothe, Sebastian Isbaner, Xiaoyun Chen, Shreya Venkatesan, Igor Kagan, Alexander Gail, Nivedita Mani   +6 more
wiley   +1 more source

Helix-bundle and C-terminal GPCR domains differentially influence GRK-specific functions and β-arrestin-mediated regulation. [PDF]

Nat Commun
Matthees ESF, Haider RS, Klement L, Reichel M, Blum NK, Weitzel V, Trüpschuch T, Ziegler C, Drube J, Schulz S, Hoffmann C.   +10 more
europepmc   +1 more source

Magnetostratigraphy and Source Characterisation Across the Early Miocene Unconformity, Northern Rocky Mountains, USA

Terra Nova, Volume 38, Issue 1, Page 1-8, February 2026.
ABSTRACT The early Miocene unconformity (EMU) formed during a transition in the tectonic regime of western North America that coincided with faunal diversification. The Railroad Canyon section in the northern Rocky Mountains provides a complete geologic record around this event. Our new magnetostratigraphic study in combination with published U‐Pb ages
Dieke Gerritsen, Stuart A. Gilder, Alina L. Ludat, Michael R. Wack   +3 more
wiley   +1 more source

Reaction of Blatter and Verdazyl Radicals with Arynes: Synthesis and Investigation of N-Chiral, Antiaromatic Triazines, and Tetrazinones. [PDF]

Angew Chem Int Ed Engl
Lezius L, Horst ES, Scherübl M, Lammert J, Daniliuc CG, Mori T, Yamaguchi S, Studer A.   +7 more
europepmc   +1 more source

Receptor‐Dependent and ‐Independent Effects of Hemin on Platelet Plasma Membrane Disintegration

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Microhemorrhages lead to the release of erythrocytes, which are then degraded and lysed. These hemolyses result in the liberation of free iron‐containing hemin. Hemin induces platelet activation and ferroptosis. Inhibition of GPVI/CLEC‐2 receptor‐mediated ITAM‐signaling inhibits hemin‐induced platelet activation (low hemin concentrations). Deferoxamine,
Zoi Laspa, Anne‐Katrin Rohlfing, Ravi Hochuli, Pamela Weronika Sowa, Tatsiana Castor, Meinrad Paul Gawaz   +5 more
wiley   +1 more source

Deciphering Ball Milling Mechanochemistry via Molecular Simulations of Collision-Driven and Liquid-Assisted Reactivity. [PDF]

Angew Chem Int Ed Engl
Gayen R, Vugrin L, Zhang Z, Hantal G, Halasz I, Smith AS.   +5 more
europepmc   +1 more source

Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Mutations in GNAO1, the gene encoding Gαo, are associated with a wide range of neurodevelopmental disorders. In this study, we show that Gαo variants linked to the most severe patient phenotypes fail to disengage from activated Gi/o‐coupled GPCRs, thereby blocking GRK‐mediated receptor phosphorylation and internalization.
Yonika A. Larasati, Camille Rabesahala de Meritens, Miriam Stoeber, Vladimir L. Katanaev, Gonzalo P. Solis   +4 more
wiley   +1 more source

SRBIJA I EVROPSKA UNIJA – KRIZE POSLE KRIZE

Srpska Politička Misao, 2011
Snežana Grk
doaj   +1 more source

The slit diaphragm in Drosophila exhibits a bilayered, fishnet architecture. [PDF]

Nat Commun
Moser D, Lang K, Birtasu AN, Grahammer F, Helmstädter M, Scheffer MP, Hermle T, Frangakis AS.   +7 more
europepmc   +1 more source