Results 71 to 80 of about 4,151 (197)
Chemistry – A European Journal, EarlyView.T‐shaped bolapolyphiles with highly branched carbosilane‐based side‐groups self‐assemble into liquid crystalline honeycombs composed of type‐2 pentagonal prismatic cells and p2gg plane group symmetry. ABSTRACT Periodic pentagon tessellations are rarely observed in self‐assembled molecular systems.
Christian Anders +3 more
wiley +1 more source
GRKs and β-Arrestins: “Gatekeepers” of Mitochondrial Function in the Failing Heart [PDF]
Frontiers in Pharmacology, 2019 Mitochondrial regulation of energy production, calcium homeostasis, and cell death are critical for cardiac function. Accordingly, the structural and functional abnormalities of these organelles (mitochondrial dysfunction) contribute to developing cardiovascular diseases and heart failure.
Sorriento, Daniela +4 more
openaire +4 more sources
Chemistry – A European Journal, EarlyView.Proximal steric tuning of quinoxaline‐fused pyrene heteroacenes enables soluble derivatives that exhibit solid‐state photoluminescence quantum yields (PLQYs) up to 82%, surpassing previous benchmarks. This work reveals key structure–property relationships for next‐generation, processable organic emitters in advanced optoelectronic applications ...
Rafiq Ahamed +9 more
wiley +1 more source
Diboron‐Embedded Heteroacenes With Systematically Varied Central π‐Skeletons and Fusion Modes
Helvetica Chimica Acta, EarlyView.We synthesized diboron‐embedded acenes and revealed that fusion mode governs electronic properties, whereas molecular symmetry dictates crystal packing. One C2v‐symmetric isomer forms a uniform columnar π‐stacked array. ABSTRACT Diboron‐embedded heteroacenes with systematically varied central π‐skeletons and fusion modes were synthesized via one‐pot ...
Tatsuya Mori +5 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.The SAAD‐41 is a 41‐item scale developed to comprehensively assess Alopecia Areata psychosocial patient‐reported outcomes. Results support scoring the scale at the subdomain level and provisionally at the total‐score level. The total‐score can be calculated as a sum of the 41 SAAD items, with the sum referred to as the SAAD‐41‐Total.
Kristina Gorbatenko‐Roth +5 more
wiley +1 more source
An Adaptive Multiple Shooting Strategy for Optimal Control
Optimal Control Applications and Methods, EarlyView.We study how multiple shooting affects the convergence of Newton‐type methods for optimal control, comparing several shooting strategies across 40 benchmark problems. The study covers interior‐point and sequential quadratic programming methods with both Quasi‐Newton approximations and exact Hessians.
Robert Lampel, Sebastian Sager
wiley +1 more source
G protein—coupled receptor kinase (GRK)
Folia Pharmacologica Japonica, 2010 Gタンパク質共役受容体キナーゼ（G Protein-coupled Receptor Kinase: GRK）の分子機能，分子構造，生理的役割を解説する．GRKは，Gタンパク質共役受容体（G Protein-Coupled Receptor: GPCR）をリン酸化するセリン・トレオニンキナーゼである．基本的な作用機構は，(1)アゴニスト結合した受容体（GPCR）がGRKを活性化，(2)活性化されたGRKが受容体をリン酸化，(3)リン酸化された受容体にアレスチン（arrestin）が結合，(4)その結果受容体の脱感受性（desensitization）が起こる，というものである．脱感受性は，受容体とGタンパク質との相互作用が損なわれる脱共役（uncoupling），受容体の細胞内への移行 ...
openaire +3 more sources
Remote Sensing in Ecology and Conservation, EarlyView.Remote sensing can reveal population dynamics of Antarctic penguin colonies. In this study, we analyze emperor penguin (Aptenodytes forsteri) guano stains in remote sensing imagery and discover colony presence predating known records for 18 colonies across Antarctica.
Martynas Bielinis +3 more
wiley +1 more source
grk-2 acts in command interneurons to regulate crawling.
, 2023 grk-2 cDNA expression in command interneurons (Pnmr-1, transgene yakSi32) is sufficient to rescue the slow locomotion of grk-2(gk268) mutant animals. (****, P0.05. One way ANOVA followed by a Bonferroni test. Error bars = SEM; n = 20). (PDF)
David M. Raizen (8742261) +6 more
core +1 more source
Small, EarlyView.Scaling nanofluidic channel geometries to sub‐200 nm is demonstrated to suppress junction guiding errors in network‐based biocomputing. The resulting increase in path fidelity enables experimental solution of Exact Cover instances with more than 33 million possible solutions, establishing a new benchmark for network‐based biocomputing. ABSTRACT Network‐
Eugene Christo V R +8 more
wiley +1 more source