Results 91 to 100 of about 4,151 (197)
The potential for biased signalling in the P2Y receptor family of GPCRs
British Journal of Pharmacology, EarlyView.The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk +2 more
wiley +1 more source
Skenario Mitigasi Gas Rumah Kaca: Studi Kasus Pengurangan Emisi Kota Probolinggo
Jurnal Wilayah dan LingkunganPerubahan iklim berdampak luas terhadap sektor lingkungan, sosial, dan ekonomi, serta berpotensi mengganggu stabilitas pembangunan jangka panjang.
Adjie Pamungkas +6 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov +2 more
wiley +1 more source
ANALISIS EMISI GAS RUMAH KACA (GRK) DAN PEMETAAN ZONA EMISI MENGGUNAKAN GIS (GEOSPASIAL INFORMATION SYSTEM) DI KABUPATEN PRINGSEWU, LAMPUNG [PDF]
, 2018 Emisi gas rumah kaca (GRK) menjadi perhatian seluruh dunia, baik itu dalam proses pengurangan ataupun pencegahan. Emisi gas rumah kaca (GRK) dapat dihasilkan dari beberapa aktifitas seperti pertanian, peternakan, transportasi dan yang tidak kalah penting
Sinthiya, Ida Ayu Putu Anggie; STMIK Pringsewu +1 more
core +1 more source
Omics Fusion – A Platform for Integrative Analysis of Omics Data
Journal of Integrative Bioinformatics, 2016 We present Omics Fusion, a new web-based platform for integrative analysis of omics data. Omics Fusion provides a collection of new and established tools and visualization methods to support researchers in exploring omics data, validating results or ...
Brink Benedikt G. +4 more
doaj +1 more source
The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment
British Journal of Pharmacology, EarlyView.Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton +6 more
wiley +1 more source
RAMS-pilotti : vaihteen sähkökääntölaitteiden kunnossapito [PDF]
, 2022 Insinöörityön tavoitteena oli tehdä pilotointi RAMS-ideologian käyttöönotosta Kuuran kunnossapitoalueelle Uudellemaalle. Pilotointi tehtiin vaihteen sähkökääntölaitteen kunnossapidosta.
Nikkinen, Satu
core
Plant, Cell &Environment, EarlyView.ABSTRACT Iron (Fe) homeostasis is regulated to prevent iron imbalance, with the help of redundant basic helix‐loop‐helix (bHLH) IVc transcription factors that can be controlled by Fe‐binding E3 ligases such as BRUTUS (BTS) in Arabidopsis thaliana.
Dibin Baby +5 more
wiley +1 more source
Saimaan kanavan alapuolisen sulun porttilehtien tiiveyteen vaikuttavat tekijät [PDF]
, 2020 Opinnäytetyö on tehty osana GRK Oy:n Saimaan kanavan alaporttilehtien uusimisurakkaa ja työ käsittelee Saimaan kanavasulkujen porttilehtien asennusta rakennussuunnitelmaselostukseen nojaten.
Jerkku, Aleksi
core
Vesihuoltolinjaston rakentaminen paalulaatalle ja sen työmaatekniset edellytykset [PDF]
, 2021 Tässä opinnäytetyössä paneuduttiin vesihuoltolinjaston rakentamiseen paalulaatalle, sekä tämän työtehtävän vaatimiin työmaateknisiin edellytyksiin. Työ on raportinomainen laaja ohjekortti, jonka konkreettinen materiaali ja esimerkit ovat peräisin GRK:n ...
Saukkola, Jesse
core