Results 81 to 90 of about 35,246 (224)
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Structural Completeness of a Multi-channel Linear System with Dependent Parameters
It is well known that the "fixed spectrum" {i.e., the set of fixed modes} of a multi-channel linear system plays a central role in the stabilization of such a system with decentralized control.
Liu, Fengjiao, Morse, A. Stephen
core
Beyond Silicon: Toward Sustainable, NIR‐II, and Conformable Organic Photodiodes
In this perspective, a strategic shift in organic photodetector (OPD) research is proposed: instead of the incremental advances in silicon's stronghold arena, the most impactful future for OPDs lies in addressing silicon's intrinsic limitations, i.e., detection in the longer wavelength range above silicon's coverage (>1100 nm, termed as near infrared ...
Hrisheekesh Thachoth Chandran +7 more
wiley +1 more source
Free analysis and planar algebras
We study 2-cabled analogs of Voiculescu's trace and free Gibbs states on Jones planar algebras. These states are traces on a tower of graded algebras associated to a Jones planar algebra.
Curran, S. +2 more
core
Abstract Objective This study was undertaken to evaluate whether synaptic vesicle protein 2A (SV2A) expression on peripheral immune cells predicts treatment response to levetiracetam in epilepsy. Methods High‐dimensional flow cytometry was used to prospectively assess SV2A expression on immune cells from levetiracetam responders, nonresponders, and ...
Johannes Lang +4 more
wiley +1 more source
Estimasi Emisi Gas Rumah Kaca (GRK) dari Sektor Peternakan Tahun 2016 di Provinsi Sulawesi Tengah
Peternakan adalah salah satu sektor yang berkontribusi dalam peningkatan pemanasan global yang berasal dari kotoran dan ekstraksi hewan. Sektor peternakan menyumbang gas metana (CH4), dinitrogen oksida (N2O), karbon dioksida (CO2), dan amonia yang dapat ...
A. B. L. Ishak, M. Takdir , Wardi Wardi
doaj +1 more source
Leaving‐group–free electron donor–acceptor (EDA) complexes have emerged as a practical platform for photocatalyst‐free radical generation under visible light. This review highlights recent advances in coupling and cyclization reactions driven by such EDA complexes, emphasizing their atom‐economical and sustainable feature.
Wenheng Liu, Line Næsborg
wiley +1 more source
Photocaged and Water‐Soluble Glucose Functionalization for Spatiotemporal Acidification Pathways
Light‐controlled glucose release from a water‐soluble coumarin photocage enables spatiotemporal acid generation in enzyme‐driven chemical reaction networks. ABSTRACT The spatiotemporal control of complex molecular systems, such as chemical reaction networks (CRNs), requires reagents and reactive species that can be activated both efficiently and ...
Nikolai Hempel +2 more
wiley +1 more source
ABSTRACT The minimum s$$ s $$‐t$$ t $$‐cut problem is one of the most‐studied problems in discrete optimization and has a unique complexity status in multi‐objective optimization. Even though the single‐objective version of the problem can be solved in polynomial time, it has been shown in the seminal work of Papadimitriou and Yannakakis (2000) that ...
Jan Boeckmann +4 more
wiley +1 more source
Abstract Objective In an aging population, patients undergoing thyroidectomy and parathyroidectomy are at an increased risk of adverse outcomes; thus, measuring patient frailty is a key metric to assess risk. This study innovatively compares the utility of the Risk Analysis Index (RAI) with the 5‐factor Modified Frailty Index (mFI‐5) in predicting ...
Akshay Warrier +7 more
wiley +1 more source

