Results 91 to 100 of about 21,316 (231)

Epitopes of Immunoreactive Proteins of Streptococcus Agalactiae: Enolase, Inosine 5′-Monophosphate Dehydrogenase and Molecular Chaperone GroEL

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Three Streptococcus agalactiae (group B streptococci, GBS) immunoreactive proteins: enolase (47.4 kDa), inosine 5′-monophosphate dehydrogenase (IMPDH) (53 kDa) and molecular chaperone GroEL (57 kDa) were subjected to investigation.
Anna Dobrut   +7 more
doaj   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin   +6 more
wiley   +1 more source

Immunization using GroEL decreases Clostridium difficile intestinal colonization. [PDF]

open access: yesPLoS ONE, 2013
Clostridium difficile is a pathogen which is responsible for diarrhea and colitis, particularly after treatment with antibiotics. Clinical signs are mainly due to two toxins, TcdA and TcdB.
Séverine Péchiné   +4 more
doaj   +1 more source

Assessment of Pathogen Contamination in Food at Teaching Hospitals in Mashhad, Iran: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Infectious diseases in hospitals pose a significant threat, with some linked to contaminated food. Food safety is a critical issue for hospital patients, particularly those with weakened immune systems. This study aimed to conduct the first comprehensive microbial evaluation of hospital catering across 12 teaching hospitals
Mojtaba Raeisi   +6 more
wiley   +1 more source

DnaK Functions as a Central Hub in the E. coli Chaperone Network

open access: yesCell Reports, 2012
Cellular chaperone networks prevent potentially toxic protein aggregation and ensure proteome integrity. Here, we used Escherichia coli as a model to understand the organization of these networks, focusing on the cooperation of the DnaK system with the ...
Giulia Calloni   +8 more
doaj   +1 more source

Burden and Correlates of Multiple Chronic Infections and Their Associations With Cancer Incidence in Chinese Adults: A Large Case‐Cohort Study

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page 1282-1295, 1 September 2026.
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang   +212 more
wiley   +1 more source

A protein chaperone can stabilize the intein‐containing precursor to indirectly promote protein splicing

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Intervening proteins (inteins) interrupt host protein sequences and are removed by a self‐mediated protein splicing reaction. Inteins are abundant in the microbial world and are often found within essential genes involved in DNA replication, recombination, and repair.
John S. Smetana   +7 more
wiley   +1 more source

Protective Effect of Recombinant Proteins of Cronobacter Sakazakii During Pregnancy on the Offspring

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Cronobacter sakazakii is a food-borne pathogen carried in milk powder that can cause severe bacteremia, enterocolitis, and meningitis in newborns, which can lead to death of newborns.
Jia-rong Song   +6 more
doaj   +1 more source

Structural and functional insights into Pseudomonas aeruginosa ApaH, a diadenosine tetraphosphatase crucial for bacterial virulence

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Infections by Pseudomonas aeruginosa are a major cause of severe morbidity and mortality in immunocompromised patients and people with cystic fibrosis, largely due to the pathogen's ability to resist antibiotic treatment and to deploy multiple virulence strategies that promote persistence in the host.
Gianluca Pistoia   +12 more
wiley   +1 more source

Identification and characterization of a Streptococcus equi ssp. zooepidemicus immunogenic GroEL protein involved in biofilm formation

open access: yesVeterinary Research, 2016
Streptococcus equi ssp. zooepidemicus (S. equi spp. zooepidemicus) is an opportunistic pathogen that causes major economic losses in the swine industry in China and is also a threat for human health.
L. Yi   +7 more
semanticscholar   +1 more source

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