Results 71 to 80 of about 19,683 (209)

The Hydrophobic Nature of GroEL-Substrate Binding [PDF]

Journal of Biological Chemistry, 1995
The molecular chaperone GroEl from Escherichia coli is a member of the highly conserved Hsp60 family of proteins that facilitates protein folding. A central question regarding the mechanism of GroEL-assisted refolding of proteins concerns its broad substrate specificity.
Z, Lin, F P, Schwartz, E, Eisenstein
openaire   +2 more sources

Using groEL as the target for identification of Enterococcus faecium clades and 7 clinically relevant Enterococcus species

Journal of Microbiology, Immunology and Infection, 2019
Background/Purpose: Accurate identification is important for effective treatment because Enterococcus species have talents to cope with various antibiotics either by intrinsic resistance or by acquisition of mobile genetic elements.
Wei-Wen Hung, Yen-Hsu Chen, Sung-Pin Tseng, Ya-Ting Jao, Lee-Jene Teng, Wei-Chun Hung   +5 more
doaj   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Revealing taxonomy, activity, and substrate assimilation in mixed bacterial communities by GroEL-proteotyping-based stable isotope probing

iScience
Summary: Protein-based stable isotope probing (protein-SIP) can link microbial taxa to substrate assimilation. Traditionally, protein-SIP requires a sample-specific metagenome-derived database for samples with unknown composition. Here, we describe GroEL-
Simon Klaes, Shobhit Madan, Darja Deobald, Myriel Cooper, Lorenz Adrian   +4 more
doaj   +1 more source

Genetic variation, phylogenetic relationship and spatial distribution of ‘Candidatus Phytoplasma ulmi’ strains in Germany

Scientific Reports, 2020
A recent survey in Germany revealed the wide presence of ‘Candidatus Phytoplasma ulmi’ in native elm stands. Accessions were studied for their genetic variability and phylogenetic relationship based on the conserved groEL and the variable imp gene. While
B. Schneider, B. Hüttel, C. Zübert, M. Kube   +3 more
doaj   +1 more source

First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique

Mass Spectrometry Reviews, Volume 45, Issue 6, Page 1064-1086, November/December 2026.
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley   +1 more source

Epitopes of Immunoreactive Proteins of Streptococcus Agalactiae: Enolase, Inosine 5′-Monophosphate Dehydrogenase and Molecular Chaperone GroEL

Frontiers in Cellular and Infection Microbiology, 2018
Three Streptococcus agalactiae (group B streptococci, GBS) immunoreactive proteins: enolase (47.4 kDa), inosine 5′-monophosphate dehydrogenase (IMPDH) (53 kDa) and molecular chaperone GroEL (57 kDa) were subjected to investigation.
Anna Dobrut, Ewa Brzozowska, Sabina Górska, Marcelina Pyclik, Andrzej Gamian, Małgorzata Bulanda, Elzbieta Majewska, Monika Brzychczy-Włoch   +7 more
doaj   +1 more source

Immunization using GroEL decreases Clostridium difficile intestinal colonization. [PDF]

PLoS ONE, 2013
Clostridium difficile is a pathogen which is responsible for diarrhea and colitis, particularly after treatment with antibiotics. Clinical signs are mainly due to two toxins, TcdA and TcdB.
Séverine Péchiné, Claire Hennequin, Céline Boursier, Sandra Hoys, Anne Collignon   +4 more
doaj   +1 more source

Extracellular Vesicle‐Encapsulated Small RNAs From Clostridium Butyricum Modulate Host Intestinal Lipid Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Extracellular vesicles (EVs) derived from C. butyricum can enter intestinal epithelial cells and mediate the anti‐lipid absorption effects by delivering miRNA‐like RNAs (milRNAs), particularly milRNA‐3020179, which primarily targeted host genes majorly including PPARα. Deletion of milRNA‐3020179 in C. butyricum abolished its effects on lipid deposition
Hong Hu, Yiwen He, Jing Liang, Qi Han, Xuqing Liang, Guangtian Cao, Yulong Tang, Liuqin He, Yulong Yin, Xihong Zhou   +9 more
wiley   +1 more source

클로렘페니콜 아세틸 전이효소 활성과 GroEL

, 1991
학위논문(박사) - 한국과학기술원 : 생물공학과, 1991.8, [ x, 136 p. ]Several proteins were overproduced by the powerful T7 expression system, and their solubility and enzyme activity were detemined.
김한복, Kim, Han-Bok
core   +1 more source