Results 71 to 80 of about 21,316 (231)

Novel cryo-EM structure of an ADP-bound GroEL–GroES complex

Scientific Reports, 2021
The GroEL–GroES chaperonin complex is a bacterial protein folding system, functioning in an ATP-dependent manner. Upon ATP binding and hydrolysis, it undergoes multiple stages linked to substrate protein binding, folding and release.
Sofia S. Kudryavtseva, Evgeny B. Pichkur, Igor A. Yaroshevich, Aleksandra A. Mamchur, Irina S. Panina, Andrei V. Moiseenko, Olga S. Sokolova, Vladimir I. Muronetz, Tatiana B. Stanishneva-Konovalova   +8 more
doaj   +1 more source

Discovery of edodine, a natural compound from Lentinula edodes with antibacterial activity for the biological control of fire blight pathogen Erwinia amylovora

Pest Management Science, EarlyView.
Novel edodine was identified from Lentinula edodes HK761, exhibiting biocontrol potential against fire blight by affecting motility, intracellular ATP level, and cell division of Erwinia amylovora. Abstract BACKGROUND In the search for biological resources with antibacterial activity against Erwinia amylovora, the culture filtrate of Lentinula edodes ...
Yeong Seok Kim, Jae Woo Han, Bomin Kim, Chunggeon Lee, Daeui Park, Jaehyuk Choi, Gyung Ja Choi, Hun Kim   +7 more
wiley   +1 more source

Local energetic frustration affects the dependence of green fluorescent protein folding on the chaperonin GroEL

Journal of Biological Chemistry, 2017
The GroE chaperonin system in Escherichia coli comprises GroEL and GroES and facilitates ATP-dependent protein folding in vivo and in vitro. Proteins with very similar sequences and structures can differ in their dependence on GroEL for efficient folding.
B. Bandyopadhyay, A. Goldenzweig, T. Unger, Orit Adato, S. Fleishman, R. Unger, A. Horovitz   +6 more
semanticscholar   +1 more source

The Hydrophobic Nature of GroEL-Substrate Binding [PDF]

Journal of Biological Chemistry, 1995
The molecular chaperone GroEl from Escherichia coli is a member of the highly conserved Hsp60 family of proteins that facilitates protein folding. A central question regarding the mechanism of GroEL-assisted refolding of proteins concerns its broad substrate specificity.
Z, Lin, F P, Schwartz, E, Eisenstein
openaire   +2 more sources

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

VIEW, EarlyView.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin, Lijie Ma, Yuqing Yuan, Kaiyi Zhu, Zhaohui Tong, Qianmei Sun   +5 more
wiley   +1 more source

Визначення та характеристика факторів ризику виникнення невиношування вагітності в жінок першого триместру гестації

Український журнал Здоров'я жінки
Ультразвукове дослідження (УЗД) відіграє вагому роль у діагностуванні загрози переривання вагітності (ЗПВ). Зміна структури міометрію, патологічні ЕХО-включення, морфологічні зміни додатків, вкорочення довжини шийки матки, відкриття внутрішнього вічка ...
N.A. Rynda-Dzuriy, D.O. Govsieiev
doaj   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

Insect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn, Vicky L. Tolmay, Marlon‐Schylor Luke le Roux, Lintle Mohase, Mpho S. Mafa, Vittorio F. Nicolis, Eduard Venter, Nicolaas Francois Visser Burger, Anna‐Maria Botha   +8 more
wiley   +1 more source

Сироваткові рівні HSP60 і GroEL як біомаркери ризику невиношування вагітності в жінок І триместру гестації

Український журнал Перинатологія і педіатрія
Невиношування вагітності (НВ) залишається однією з провідних причин репродуктивних втрат у світі та в Україні. Незважаючи на прогрес у пренатальному діагностуванні, у 40–50% випадків етіологія НВ не встановлена, що підкреслює потребу в нових біомаркерах.
D.O. Govsieiev, N.A. Rynda-Dzyuriy, L.I. Martynova, O.L. Gromova   +3 more
doaj   +1 more source

Dataset concerning GroEL chaperonin interaction with proteins

Data in Brief, 2016
GroEL chaperonin is well-known to interact with a wide variety of polypeptide chains. Here we show the data related to our previous work (http://dx.doi.org/10.1016/j.pep.2015.11.020 [1]), and concerning the interaction of GroEL with native (lysozyme, α ...
V.V. Marchenkov, N.Yu. Marchenko, A.L. Kaysheva, N.V. Kotova, I.A. Kashparov, G.V. Semisotnov   +5 more
doaj   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source