Results 81 to 90 of about 19,683 (209)

DnaK Functions as a Central Hub in the E. coli Chaperone Network

open access: yesCell Reports, 2012
Cellular chaperone networks prevent potentially toxic protein aggregation and ensure proteome integrity. Here, we used Escherichia coli as a model to understand the organization of these networks, focusing on the cooperation of the DnaK system with the ...
Giulia Calloni   +8 more
doaj   +1 more source

The Roles of Contrasting Host Types on the Environmental Abundance of Anaplasma phagocytophilum, an Emerging Zoonotic Pathogen

open access: yesEcology and Evolution, Volume 16, Issue 9, September 2026.
In this study, we analysed data collected at 40 sites in the Northwest of Scotland (from 2018 to 2020) to quantify the relative contributions of hypothesised pathogen transmission hosts (deer and sheep) and non‐transmission hosts (birds and rodents) on the environmental abundance of ecotypes I and II of Anaplasma phagocytophilum. Our results add to our
William McLellan   +8 more
wiley   +1 more source

ROLE OF SALT BRIDGES IN GROEL ALLOSTERY [PDF]

open access: yes, 2014
Chaperonin GroEL facilitates protein folding with two stacked back-to-back, identical rings and the "lid", co-chaperonin GroES. The mis-folded/unfolded substrate protein (SP) adjusts the chaperonin cycling from an asymmetric to a symmetric cycle by ...
Yang, Dong
core   +1 more source

In Vitro Characterization of Technological and Health‐Promoting Properties of Enterocin Producing Lactic Acid Bacteria From Camel Milk and Its Suitability as a Dairy Starter

open access: yesFood Chemistry International, Volume 2, Issue 3, Page 398-410, September 2026.
Enterocin‐producing Enterococcus faecium RSCUDR7 from camel milk exhibited strong probiotic and antimicrobial properties, along with stability in skim milk. Its suitability as a safe and effective dairy starter highlights its potential for developing functional probiotic dairy products.
Rahul Singhal   +4 more
wiley   +1 more source

Chaperonins GroEL and GroES: views from atomic force microscopy [PDF]

open access: yes, 1996
The Escherichia coli chaperonins, GroEL and GroES, as well as their complexes in the presence of a nonhydrolyzable nucleotide AMP-PNP, have been imaged with the atomic force microscope (AFM).
Mou, J., Ho, R., Shao, Z., Sheng, S.
core   +1 more source

Assessment of Pathogen Contamination in Food at Teaching Hospitals in Mashhad, Iran: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Infectious diseases in hospitals pose a significant threat, with some linked to contaminated food. Food safety is a critical issue for hospital patients, particularly those with weakened immune systems. This study aimed to conduct the first comprehensive microbial evaluation of hospital catering across 12 teaching hospitals
Mojtaba Raeisi   +6 more
wiley   +1 more source

Allosteric differences dictate GroEL complementation of E. coli

open access: yes, 2022
GroES/GroEL is the only bacterial chaperone essential under all conditions, making it a potential antibiotic target. Rationally targeting ESKAPE GroES/GroEL as an antibiotic strategy necessitates studying their structure and function.
Marty, Michael T.   +16 more
core   +1 more source

In silico engineering of aggregation-prone recombinant proteins for substrate recognition by the chaperonin GroEL

open access: yesBMC Genomics, 2012
Background Molecular chaperones appear to have been evolved to facilitate protein folding in the cell through entrapment of folding intermediates on the interior of a large cavity formed between GroEL and its co-chaperonin GroES.
Kumar Vipul   +3 more
doaj   +1 more source

Protective Effect of Recombinant Proteins of Cronobacter Sakazakii During Pregnancy on the Offspring

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Cronobacter sakazakii is a food-borne pathogen carried in milk powder that can cause severe bacteremia, enterocolitis, and meningitis in newborns, which can lead to death of newborns.
Jia-rong Song   +6 more
doaj   +1 more source

Burden and Correlates of Multiple Chronic Infections and Their Associations With Cancer Incidence in Chinese Adults: A Large Case‐Cohort Study

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page 1282-1295, 1 September 2026.
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang   +212 more
wiley   +1 more source

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