Results 81 to 90 of about 19,683 (209)
DnaK Functions as a Central Hub in the E. coli Chaperone Network
Cellular chaperone networks prevent potentially toxic protein aggregation and ensure proteome integrity. Here, we used Escherichia coli as a model to understand the organization of these networks, focusing on the cooperation of the DnaK system with the ...
Giulia Calloni +8 more
doaj +1 more source
In this study, we analysed data collected at 40 sites in the Northwest of Scotland (from 2018 to 2020) to quantify the relative contributions of hypothesised pathogen transmission hosts (deer and sheep) and non‐transmission hosts (birds and rodents) on the environmental abundance of ecotypes I and II of Anaplasma phagocytophilum. Our results add to our
William McLellan +8 more
wiley +1 more source
ROLE OF SALT BRIDGES IN GROEL ALLOSTERY [PDF]
Chaperonin GroEL facilitates protein folding with two stacked back-to-back, identical rings and the "lid", co-chaperonin GroES. The mis-folded/unfolded substrate protein (SP) adjusts the chaperonin cycling from an asymmetric to a symmetric cycle by ...
Yang, Dong
core +1 more source
Enterocin‐producing Enterococcus faecium RSCUDR7 from camel milk exhibited strong probiotic and antimicrobial properties, along with stability in skim milk. Its suitability as a safe and effective dairy starter highlights its potential for developing functional probiotic dairy products.
Rahul Singhal +4 more
wiley +1 more source
Chaperonins GroEL and GroES: views from atomic force microscopy [PDF]
The Escherichia coli chaperonins, GroEL and GroES, as well as their complexes in the presence of a nonhydrolyzable nucleotide AMP-PNP, have been imaged with the atomic force microscope (AFM).
Mou, J., Ho, R., Shao, Z., Sheng, S.
core +1 more source
ABSTRACT Background and Aims Infectious diseases in hospitals pose a significant threat, with some linked to contaminated food. Food safety is a critical issue for hospital patients, particularly those with weakened immune systems. This study aimed to conduct the first comprehensive microbial evaluation of hospital catering across 12 teaching hospitals
Mojtaba Raeisi +6 more
wiley +1 more source
Allosteric differences dictate GroEL complementation of E. coli
GroES/GroEL is the only bacterial chaperone essential under all conditions, making it a potential antibiotic target. Rationally targeting ESKAPE GroES/GroEL as an antibiotic strategy necessitates studying their structure and function.
Marty, Michael T. +16 more
core +1 more source
Background Molecular chaperones appear to have been evolved to facilitate protein folding in the cell through entrapment of folding intermediates on the interior of a large cavity formed between GroEL and its co-chaperonin GroES.
Kumar Vipul +3 more
doaj +1 more source
Protective Effect of Recombinant Proteins of Cronobacter Sakazakii During Pregnancy on the Offspring
Cronobacter sakazakii is a food-borne pathogen carried in milk powder that can cause severe bacteremia, enterocolitis, and meningitis in newborns, which can lead to death of newborns.
Jia-rong Song +6 more
doaj +1 more source
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang +212 more
wiley +1 more source

