Results 1 to 10 of about 23,956 (223)

Bone morphology and alignment features are associated with knee kinematics in healthy individuals: A scoping review [PDF]

Journal of Experimental Orthopaedics
Purpose The aim of this scoping review was to compose an overview of existing literature on the influence of knee bone morphology and alignment on knee kinematics in healthy individuals.
Erin Teule, Sebastiaan van de Groes, Nico Verdonschot, Dennis Janssen   +3 more
doaj   +3 more sources

Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL

MBio, 2021
The GroES/GroEL chaperonin from E ...
Jared Sivinski, Andrew J Ambrose, Praechompoo Pongtornpipat   +2 more
exaly   +3 more sources

Screening of molecular elements and improvement of heat resistance in a thermophilic bacterium [PDF]

Engineering Microbiology
Engineering microorganisms to withstand extreme temperatures (>80 °C) remains a critical challenge in industrial biotechnology owing to limited genetic tools and poor mechanistic understanding of microbial thermoadaptation.
Jie Cui, Caifeng Li, Gongze Cao, Yuxia Wu, Shouying Xu, Youming Zhang, Xiaoying Bian, Qiang Tu, Wentao Zheng   +8 more
doaj   +2 more sources

The trajectory of conditional, recurrence-free, and long-term survival in a complete 10-year cohort of patients with advanced ovarian cancer [PDF]

Acta Oncologica
Background: The prognosis in advanced ovarian cancer is generally poor since the majority experience recurrence. Nevertheless, there is a chance of cure and very long-term survival may be achieved. However, traditional survival metrics do not account for
Nina Groes Kofoed, Henrik Falconer, Matteo Bottai, Sahar Salehi   +3 more
doaj   +2 more sources

Formation of the chaperonin complex studied by 2D NMR spectroscopy. [PDF]

PLoS ONE, 2017
We studied the interaction between GroES and a single-ring mutant (SR1) of GroEL by the NMR titration of 15N-labeled GroES with SR1 at three different temperatures (20, 25 and 30°C) in the presence of 3 mM ADP in 100 mM KCl and 10 mM MgCl2 at pH 7.5.
Toshio Takenaka, Takashi Nakamura, Saeko Yanaka, Maho Yagi-Utsumi, Mahesh S Chandak, Kazunobu Takahashi, Subhankar Paul, Koki Makabe, Munehito Arai, Koichi Kato, Kunihiro Kuwajima   +10 more
doaj   +1 more source

In vivo client proteins of the chaperonin GroEL-GroES provide insight into the role of chaperones in protein evolution

Frontiers in Molecular Biosciences, 2023
Protein folding is often hampered by intermolecular protein aggregation, which can be prevented by a variety of chaperones in the cell. Bacterial chaperonin GroEL is a ring-shaped chaperone that forms complexes with its cochaperonin GroES, creating ...
Hideki Taguchi, Ayumi Koike-Takeshita
doaj   +1 more source

Identification of elements that dictate the specificity of mitochondrial Hsp60 for its co-chaperonin. [PDF]

PLoS ONE, 2012
Type I chaperonins (cpn60/Hsp60) are essential proteins that mediate the folding of proteins in bacteria, chloroplast and mitochondria. Despite the high sequence homology among chaperonins, the mitochondrial chaperonin system has developed unique ...
Avital Parnas, Shahar Nisemblat, Celeste Weiss, Galit Levy-Rimler, Amir Pri-Or, Tsaffrir Zor, Peter A Lund, Peter Bross, Abdussalam Azem   +8 more
doaj   +1 more source

Back to GroEL-Assisted Protein Folding: GroES Binding-Induced Displacement of Denatured Proteins from GroEL to Bulk Solution

Biomolecules, 2020
The main events in chaperone-assisted protein folding are the binding and ligand-induced release of substrate proteins. Here, we studied the location of denatured proteins previously bound to the GroEL chaperonin resulting from the action of the GroES co-
Victor Marchenkov, Andrey Gorokhovatsky, Natalia Marchenko, Tanya Ivashina, Gennady Semisotnov   +4 more
doaj   +1 more source

Exploração ou gratidão? Patronagem íntima e a gramática moral das trocas sexuais econômicas entre jovens curtidoras e europeus mais velhos, expatriados, em Maputo – Moçambique [PDF]

Cadernos Pagu, 2016
Resumo Neste artigo exploro uma categoria particular de mulheres inserida em sistemas de intercâmbio locais assim como na paisagem urbana transnacional de trocas íntimas.
Christian Groes-Green
doaj   +3 more sources

ATTRACT-EM: a new method for the computational assembly of large molecular machines using cryo-EM maps. [PDF]

PLoS ONE, 2012
Many of the most important functions in the cell are carried out by proteins organized in large molecular machines. Cryo-electron microscopy (cryo-EM) is increasingly being used to obtain low resolution density maps of these large assemblies.
Sjoerd J de Vries, Martin Zacharias
doaj   +1 more source