Results 71 to 80 of about 27,570 (293)

The Relationship between Age at First Birth and Mother's Lifetime Earnings: Evidence from Danish Data. [PDF]

PLoS ONE, 2016
Having children creates career interruptions and reductions in labor income for women. This study documents the relation between the age at first birth (AFB) and women's labor income. We study these dynamics in the short run (i.e.
Man Yee Mallory Leung, Fane Groes, Raul Santaeulalia-Llopis   +2 more
doaj   +1 more source

Breaking barriers: transitioning from X‐ray crystallography to cryo‐EM for structural studies

Acta Crystallographica Section D, Volume 82, Issue 3, Page 253-273, March 2026.
This article describes the transition of the Glass laboratory from X‐ray crystallography to single‐particle cryo‐electron microscopy (cryo‐EM) for structural studies of ATAD2B, a large AAA+ ATPase‐ and bromodomain‐containing protein involved in chromatin regulation.
Hassan Zafar, Kiera L. Malone, Ajit K. Singh, Michael A. Cianfrocco, Karen C. Glass   +4 more
wiley   +1 more source

Use of a Chimeric Hsp70 to Enhance the Quality of Recombinant Plasmodium falciparum S-Adenosylmethionine Decarboxylase Protein Produced in Escherichia coli. [PDF]

PLoS ONE, 2016
S-adenosylmethionine decarboxylase (PfAdoMetDC) from Plasmodium falciparum is a prospective antimalarial drug target. The production of recombinant PfAdoMetDC for biochemical validation as a drug target is important.
Xolani Henry Makhoba, Adélle Burger, Dina Coertzen, Tawanda Zininga, Lyn-Marie Birkholtz, Addmore Shonhai   +5 more
doaj   +1 more source

Capturing the essence of folding and functions of biomolecules using Coarse-Grained Models

, 2011
The distances over which biological molecules and their complexes can function range from a few nanometres, in the case of folded structures, to millimetres, for example during chromosome organization. Describing phenomena that cover such diverse length,
A Dhar, A Elcock, A Elcock, A Grosberg, A Grosberg, A Minton, A Pisliakov, A Podtelezhnikov, A Rychkova, A Savelyev, A Vologodskii, AA Podtelezhnikov, B Messer, BJ Alder, C Bustamante, C Clementi, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, D Thirumalai, D Thirumalai, D Thirumalai, D Thirumalai, D Thirumalai, E Koculi, E Lieberman-Aiden, E O'Brien, E Shakhnovich, EP O'Brien, F Valle, G Lorimer, G Papoian, G Ziv, H Liu, H Ma, HX Zhou, I Tinoco Jr., J Chen, J Harms, J Karanicolas, J Straub, JD Honeycutt, JM Fernandez, JN Onuchic, KA Dill, M Levitt, M Mickler, M Strajbl, M Takano, ME Fisher, MJ Todd, MS Cheung, N Hirokawa, N Koga, N Toan, OK Dudko, P Weinkam, PB Moore, PC Whitford, Q Du, R Russell, R Tehver, R Tehver, RD Vale, RD Vale, RI Dima, RW Pastor, S Jun, S Jun, S Jun, S Kamerlin, S Kirkpatrick, S Moghaddam, SB Smith, SJ Chen, SJ Marrink, T Cloutier, T Cremer, T Kirkpatrick, T Veitshans, V Lubchenko, Z Liu, Z Xu   +89 more
core   +1 more source

Heat shock protein 10 as a chaperone modulating α‐synuclein amyloid fibril formation

Protein Science, Volume 35, Issue 2, February 2026.
Abstract HSP10 is a well‐known human co‐chaperone that interacts with HSP60 to comprise the HSP60/10 chaperonin complex which upholds mitochondrial proteostasis. HSP10 also demonstrates independent roles in binding to misfolded proteins and interacts with several amyloidogenic client proteins.
Johan N. K. Larsson, Ranjeet Kumar, Fiamma Ayelen Buratti, Sofie Nyström, Pernilla Wittung‐Stafshede, Per Hammarström   +5 more
wiley   +1 more source

Peptidic Tryptophan Halogenation by a Promiscuous Flavin‐Dependent Enzyme

Angewandte Chemie, Volume 137, Issue 42, October 13, 2025.
ChlH, a flavin‐dependent tryptophan halogenase, was reconstituted in vitro and capable of modifying a wide array of diverse peptidic substrates. This suggests a potential use in the biocatalytic production of chlorinated peptides. Abstract Amino acids undergo numerous enzymatic modifications.
Andrew J. Rice, Mayuresh G. Gadgil, Paola Bisignano, Richard A. Stein, Hassane S. Mchaourab, Douglas A. Mitchell   +5 more
wiley   +2 more sources

‘Virginity is a virtue: prevent early sex’: teacher perceptions of sex education in a Ugandan secondary school [PDF]

, 2013
Sex education is a politically contentious issue in many countries, and there are numerous, competing ideologies relating to the most appropriate methods to teach young people about sexual and reproductive health.
Aggleton, Peter, Iyer, Padmini
core   +1 more source

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 515-528, February 2026.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper, Alyssa Powers, Kevin P. Battaile, Al‐Walid Mohsen, David K. Johnson, Scott Lovell, Lina Ghaloul‐Gonzalez   +6 more
wiley   +1 more source

Determination of the Number of Active GroES Subunits in the Fused Heptamer GroES Required for Interactions with GroEL [PDF]

Journal of Biological Chemistry, 2008
A double-heptamer ring chaperonin GroEL binds denatured substrate protein, ATP, and GroES to the same heptamer ring and encapsulates substrate into the central cavity underneath GroES where productive folding occurs. GroES is a disk-shaped heptamer, and each subunit has a GroEL-binding loop.
T. Nojima, S. Murayama, MASASUKE YOSHIDA, F. Motojima   +3 more
openaire   +2 more sources

Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays.

, 2013
Campylobacter jejuni is the leading cause of human bacterial gastroenteritis worldwide, but source attribution of the organism is difficult. Previously, DNA microarrays were used to investigate isolate source, which suggested a non-livestock source of ...
Altschul, Brandl, Champion, Dingle, Dingle, Dorrell, Ethelberg, Francisco, French, Gundogdu, Harris, Hepworth, Hepworth, Hinchliffe, Howard, Huelsenbeck, Jensen, Jorgensen, Joshua, Kalendar, Karenlampi, Katoh, Katoh, Kemp, Kim, Kim, King, Kwan, Kwan, Manning, McCarthy, Mellmann, Miller, Moen, Murphy, Ogden, On, Park, Pearson, Petersen, Ronquist, Rosef, Rosef, Sails, Sanad, Schonberg-Norio, Skirrow, Skirrow, Stabler, Staden, Staden, Taboada, Taboada, Tam, Tam, Wilson   +55 more
core   +1 more source