Results 41 to 50 of about 3,321,810 (226)

Screening of gross motor skills among Swedish children and adolescents

, 2006
Screening of gross motor skills among Swedish children and adolescentsAnna Tidén, Marie NybergStockholm University College of Physical Education and Sports, SwedenPhysical Education (PE) teachers in Sweden have noticed that pupils are getting worse in ...
Tidén, Anna,, Nyberg, Marie,
core   +8 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Effect of a governmentally-led physical activity program on motor skills in young children attending child care centers: a cluster randomized controlled trial [PDF]

, 2013
OBJECTIVE: To assess the effect of a governmentally-led center based child care physical activity program (Youp'la Bouge) on child motor skills.Patients and methods: We conducted a single blinded cluster randomized controlled trial in 58 Swiss child care
Jérôme Barral, Puder, Jardena J, Tanja H Kakebeeke, Longchamp, A., Kriemler, Susi, Christian Schindler, Bonvin, A., Jardena J Puder, Puder, J.J., Anouk Longchamp, Barral, J., Marques-Vidal, Pedro, Marques-Vidal, P., Pedro Marques-Vidal, Longchamp, Anouk, Kakebeeke, Tanja H., Kakebeeke, T.H., Kriemler, S., Puder, Jardena J., Kakebeeke, Tanja H; https://orcid.org/, Barral, Jérôme, Susi Kriemler, Schindler, Christian, Antoine Bonvin, Schindler, C., Bonvin, Antoine   +25 more
core   +1 more source

Association between motor skills and executive function of children with autism spectrum disorder in Taiwan and the United States

Frontiers in Public Health
ObjectiveThe purpose of this study was to examine the relationship between parent ratings of motor skills and executive function (EF) in children with autism spectrum disorder (ASD) in the United States and Taiwan.Materials and methodOne hundred and ...
Ming-Chih Sung, Megan M. McClelland, William Massey, Samuel W. Logan, Megan MacDonald   +4 more
doaj   +1 more source

Investigation of Motor Abilities According to Gender in Children with Diplegic Cerebral Palsy

Bezmiâlem Science, 2020
Objective:The aim of this study was to compare the fine and gross motor skills of children with diplegic cerebral palsy (CP) according to gender.Methods:This study included 73 children with diplegic CP (39 males, mean age: 8.76±1.4; 34 females mean age ...
Özgün Kaya KARA, Sedef ŞAHİN, Barkın KÖSE, Hasan Atacan TONAK, Koray KARA   +4 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Assessment of Fine and Gross Motor Skills and Its Relationship with Some Anthropometric Indices and Environmental Factors among Preschool Children Aged in 3-6 in North of Tehran

Journal of Rehabilitation, 2015
Objective: One of the most important issues in the development of fundamental motor skills in the early years of life is development of fine and gross motor skills.
Hassan Kordi
doaj  

Survey of Gross Motor Skills in Students with Intellectual Disabilities Aged 6-10 Years at SLBN C Pembina Malang

Indonesian Journal of Research in Physical Education, Sport, and Health
This research was conducted because of the lack of understanding of motor skills in children with disabilities. This study aims to evaluate and understand the level of gross motor skills of students with tunagrahita in SLBN C Pembina Malang Regency.
Edo Ferdiansyah, Rama Kurniawan, Herdhika Ayu Retno Kusumasari   +2 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source