Results 51 to 60 of about 461,123 (254)

Dynamic Behavior of Pile-Supported Structures with Batter Piles according to the Ground Slope through Centrifuge Model Tests

Applied Sciences, 2020
Pile-supported structures incorporating batter piles are commonly used, and can be installed both on the horizontal and inclined ground. Recent studies have considered the positive role of batter piles during earthquakes, highlighting their satisfactory ...
Jungwon Yun, Jintae Han
doaj   +1 more source

Detection of 6 November 1997 ground level event by Milagrito [PDF]

, 2000
Solar Energetic Particles (SEPs) with energies exceeding 10 GeV associated with the 6 November 1997 solar flare/CME (coronal mass ejection) have been detected with Milagrito, a prototype of the Milagro Gamma Ray Observatory. While SEP acceleration beyond
Atkins, R, Benbow, W, Berley, D, Chen, M L, Coyne, D G, Dingus, B L, Dorfan, D E, Ellsworth, R W, Evans, D, Falcone, A, Fleysher, L, Fleysher, R, Gisler, G, Goodman, J A, Haines, T J, Hoffman, C M, Hugenberger, S, Kelley, L A, Leonor, I, Macri, John R, McConnell, Mark L, McCullough, J F, McEnery, J E, Miller, R S, Mincer, A I, Morales, M F, Nemethy, P, Ryan, James M., Shen, B, Shoup, A, Sinnis, G, Smith, A J, Sullivan, G W, Tumer, O T, Wang, K, Wascko, M O, Westerhoff, S, Williams, D A, Yang, T, Yodh, G B   +39 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

An Estimation of Earthquake Impact to Population in Makassar by Probabilistic Approach

Forum Geografi, 2016
Makassar is one of Indonesian big cities with rapid growth rate, but not totally safe from earthquake hazard. This condition led study on affected population by earthquakes in this city are important to do. This paper estimated the population of Makassar
Bambang Sunardi, Sulastri Sulastri
doaj  

Review of Seismic Characteristics in Erbil City, the Capital of the Kurdistan Region of Iraq

Polytechnic Journal, 2019
Erbil city essentially suffers from the risk of earthquakes generated by Zagros-Taurus Belt. The central objective of this study is to identify the seismic characteristics and required seismic parameters for structural analysis.
Zina A. Abdul Jaleel, Bahman O. Taha
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

High-energy gamma-rays from stellar associations [PDF]

, 2003
It is proposed that TeV gamma-rays and neutrinos can be produced by cosmic rays (CRs) through hadronic interactions in the innermost parts of the winds of massive O and B stars.
Domingo-Santamaria, Eva, Romero, Gustavo E., Torres, Diego F.   +2 more
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source