Results 111 to 120 of about 651,062 (315)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

The effect of ground-state spin on fission and quasi-fission anisotropies

, 2003
R. D. Butt
openalex   +2 more sources

Effects of ground water table and ground inclination on train induced ground-borne vibrations

, 2019
Passage of the train wheels induces ground-borne vibrations at the railwheel interface, where the main contribution is due to the axle loads moving on irregular track and wheel interface. These vibrations can cause problems such as the compaction and settlement of the foundation soil of the structures nearby, liquefaction of the soil or discomfort of ...
openaire   +3 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Effect of foresting barren ground with Macrocystis pyrifera (Linnaeus) C. Agardh on the occurrence of coastal fishes off northern Chile [PDF]

, 2018
Mario J Villegas, Jürgen Laudien, Walter Sielfeld, Wolf Arntz   +3 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Influence of Truing Condition on the Strength of Ground Ceramics Effect of Speed-ratio between Wheel and Truer.

, 1995
Meng Liu, Jun-ichiro Takagi
openalex   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Sodium Concentration in Potable Ground Water in Coastal Belt of Bangladesh Due To the Effect of Global Warming: A Potential Health Risk

, 2014
Iosr Journals, M. Kutub U Khan A. M. Tuhin-Ul Alam   +1 more
openalex   +1 more source

Long-period ground motion effect in Shaanxi Province of Changning Ms6.0 earthquake [PDF]

, 2020
Baolai Li, Fengwen Ren, Hongwu Feng, Gu Yunhe, Chun-Feng Li   +4 more
openalex   +1 more source