Results 101 to 110 of about 11,322,797 (240)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Optimization of High‑Speed WIG Airfoil with Consideration of Non‑ground Effect by a Two‑Step Deep Learning Inverse Design Method

Transactions of Nanjing University of Aeronautics and Astronautics
Under complex flight conditions， such as obstacle avoidance and extreme sea state， wing-in-ground （WIG） effect aircraft need to ascend to higher altitudes， resulting in the disappearance of the ground effect.
WANG Chenlu, SUN Jianhong, ZHENG Daren, SUN Zhi, ZUO Si, LIU Hao, LI Pei   +6 more
doaj   +1 more source

The Ground Effect in Anguilliform Swimming. [PDF]

Biomimetics (Basel), 2020
Ogunka UE, Daghooghi M, Akbarzadeh AM, Borazjani I.   +3 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A Residual PPO Method for Shipboard Helicopter Landing Control

Aerospace
Shipboard helicopter landing in the near-deck region requires stable attitude regulation and high-precision deck-relative motion control under substantial model uncertainty and environmental disturbances, conditions under which conventional model-based ...
Xiao Chang, Jianliang Ai
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Robert Ground Family Tree [PDF]

, 1937
Robert Ground and Margaret Cockeral Family Tree. This family tree chart was compiled by Mamie Ground Hays and Pleasant Ground in 1937. It was recopied in January, 1983 by Karla Ground Lowe, daughter of Clifton Ground. The chart was transcribed by Frankie
Ground, Pleasant, Hays, Mamie Ground
core  

Blade element – momentum aerodynamic model of a helicopter rotor operating at low-Reynolds numbers in ground effect

Aviation
The general objective of this paper is to present the initial results obtained as an outcome of applying a coupled Experimentally Derived – Blade Element Momentum Theory (BEMT) model for evaluating the airflow-defining parameters of a hovering ...
Gabriel Georgiev
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source