Results 121 to 130 of about 11,572,657 (308)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Ground instability effects

This chapter is conceived to describe methodologies for the generation of scenarios having as effects ground deformation processes (landslides, subsidence and underground cavity collapses) triggered by different inputs. Special attention has been devoted to products for the aware management of the territory and to define strategies for the community ...
Strom, Alexander, Marmoni, Gian Marco, Dahal, A., Tanyas, H., Lombardo, L., Delchiaro, Michele   +5 more
openaire   +2 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Computation of ground waves from pile driving and their effects on structures [PDF]

, 2002
Present guidance on levels of vibration generated by pile driving is primarily empirical, conservative and often contradictory. The objective of this research was to model the ground waves generated by pile driving using the ABAQUS finite element program
Ramshaw, Christine Lesley, Ramshaw, C.L.
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Modeling the effects of vegetation growth rate on the dynamics of alternate bars

Progress in Earth and Planetary Science
Alternate bars migrate downstream during floods due to coupled erosion and deposition on both sides of alluvial river channels. During low discharge periods, vegetation can grow on the tops of these bars, reducing migration rates and increasing bar ...
Pawat Wattanachareekul, Takuya Inoue, Joel P. L. Johnson   +2 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Study of the influence of deviations in both jacking force and cutterhead torque during shield tunnelling in soft ground

Scientific Reports
During shield tunnelling, vertical ground displacement is significantly influenced by deviations in both jacking force and cutterhead torque. This study investigates the effects of deviations in these parameters on ground displacement via numerical ...
Liang Peng, Rui Huang, Takafumi Seiki, Dongqing Nie, Satoshi Yamaoka, Qinxi Dong, Ping Lu   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Report of activities: Army ground forces, World War II.

, 2008
This is a brief report covering the world-wide activities of Army Ground Forces from its organization in March 1942 to the surrender of Japan. The table of contents includes: the American ground soldier; building the ground Army in the United States ...
Headquarters, Army Ground Forces, Office of the Commanding General
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