Results 51 to 60 of about 186,904 (313)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Motion computation and visual orientation in flies

open access: yes, 1993
Egelhaaf M, Borst A. Motion computation and visual orientation in flies. Comparative Biochemistry and Physiology, A: Comparative Physiology. 1993;104(4):659-673.Visual orientation greatly relies on the evaluation of the motion patterns received by the ...
Egelhaaf, M.   +3 more
core   +1 more source

Grouping puts figure-ground assignment in context by constraining propagation of edge assignment. [PDF]

open access: yes, 2010
Figure-ground organization involves the assignment of edges to a figural shape on one or the other side of each dividing edge. Established visual cues for edge assignment primarily concern relatively local rather than contextual factors.
Driver, Jon, Brooks, Joseph L
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Proposition of isolation system applicable to the long-period earthquake ground motion (Method of changing natural frequency of isolation system with additional spring)

open access: yesNihon Kikai Gakkai ronbunshu, 2019
At present, there are many types of isolation system, and many of them are designed for the short-period ground motion. The long-period ground motion has recently attracted the attention, though the isolation system for the short-period ground motion ...
Shozo KAWAMURA   +3 more
doaj   +1 more source

Measuring human-induced vibrations of civil engineering structures via vision-based motion tracking [PDF]

open access: yes, 2016
We present a novel framework for measuring the body motion of multiple individuals in a group or crowd via a vision-based tracking algorithm, thus to enable studies of human-induced vibrations of civil engineering structures, such as floors and ...
Racic, V.   +9 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

On the neuronal basis of figure-ground discrimination by relative motion in the visual system of the fly. 3: Possible input circuitries and behavioural significance of the FD-cells

open access: yes, 1985
Egelhaaf M. On the neuronal basis of figure-ground discrimination by relative motion in the visual system of the fly. 3: Possible input circuitries and behavioural significance of the FD-cells. Biological Cybernetics.
Egelhaaf, M.   +1 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Relationships between ground motion parameters and macroseismic intensity for Italy

open access: yes, 2020
The relation between macroseismic intensity and ground shaking makes it possible to transform instrumental Ground Motion Parameters (GMPs) in macroseismic intensity and vice versa, and is therefore useful for making comparisons between estimates of ...
Lanzano, Giovanni   +9 more
core   +1 more source

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