Results 81 to 90 of about 1,374,449 (283)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Spectral element method simulation of three-dimensional sedimentary basin under reverse-fault earthquakes

地震科学进展, 2020
Near-fault ground motion can cause serious earthquake disaster in the near-field area，especially when there is sedimentary topography in the area. At present，there are no reports on the ground motion response of sedimentary basins under the action of ...
Zhenning Ba, Jingxuan Zhao, Mengtao Wu, Jianwen Liang, La Ta   +4 more
doaj   +1 more source

Real-time seismology and earthquake damage mitigation [PDF]

, 2005
Real-time seismology refers to a practice in which seismic data are collected and analyzed quickly after a significant seismic event, so that the results can be effectively used for postearthquake emergency response and early warning.
Kanamori, Hiroo
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Rupture Directivity of Moderate Earthquakes Along the Main Marmara Fault Suggests Larger Ground Motion Towards Istanbul

Geophysical Research Letters
Analysis of earthquake rupture directivity provides key information for seismic hazard and risk assessment, particularly for faults near urban areas. We analyze directivity patterns for 31 well‐constrained ML≥ 3.5 earthquakes along the Main Marmara Fault,
Xiang Chen, Patricia Martínez‐Garzón, Grzegorz Kwiatek, Yehuda Ben‐Zion, Marco Bohnhoff, Fabrice Cotton   +5 more
doaj   +1 more source

Estimation of Seismic Loss for a Portfolio of Buildings under Bidirectional Horizontal Ground Motions due to a Scenario Cascadia Event

Frontiers in Built Environment, 2017
Earthquake ground motions induced by a scenario event are spatially (partially) correlated and (partially) coherent. Simulated ground motion records can be used to carry out nonlinear inelastic time history analysis for a portfolio of buildings to ...
Taojun Liu, Taojun Liu, Hanping Hong
doaj   +1 more source

Sideband Cooling Micromechanical Motion to the Quantum Ground State

, 2011
The advent of laser cooling techniques revolutionized the study of many atomic-scale systems. This has fueled progress towards quantum computers by preparing trapped ions in their motional ground state, and generating new states of matter by achieving ...
A Schliesser, A. J. Sirois, AA Clerk, AD O'Connell, BD Cuthbertson, CA Regal, Dale Li, DG Blair, F Diedrich, F Marquardt, I Wilson-Rae, J. D. Teufel, J. D. Whittaker, J. W. Harlow, JD Teufel, JD Teufel, JD Teufel, JD Thompson, JM Dobrindt, K Cicak, K. Cicak, K. W. Lehnert, M Hofheinz, M. S. Allman, MA Castellanos-Beltran, MH Anderson, Q Lin, R. W. Simmonds, S Bose, S Gröblacher, S Gröblacher, S Mancini, T Rocheleau, T. Donner, TJ Kippenberg, VB Braginsky, VB Braginsky, W Marshall, Y-S Park   +38 more
core   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source