Results 81 to 90 of about 314,262 (321)

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Ground-Motion Intensity Measures for the Seismic Response of the Roof-Isolated Large-Span Structure

Buildings
Ground-motion intensity measures (IMs), which quantify and describe the characteristics of earthquake ground motion, are of utmost importance in the assessment of seismic risk and the design of resilient structures with large spans.
Wei Zhen, Yikun Qiu, Yanhua Zhang, Wei Li   +3 more
doaj   +1 more source

Ground Motion Model of the SLAC Site [PDF]

eConf C000821 (2000) MOA13, 2000
We present a ground motion model for the SLAC site. This model is based on recent ground motion studies performed at SLAC as well as on historical data. The model includes wave-like, diffusive and systematic types of motion. An attempt is made to relate measurable secondary properties of the ground motion with more basic characteristics such as the ...
arxiv  

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

FEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla, Faiza Abbas, Luigia Rossi, Mauro Magnani, Sara Biagiotti   +4 more
wiley   +1 more source

Neural Network-Based Equations for Predicting PGA and PGV in Texas, Oklahoma, and Kansas [PDF]

, 2018
Parts of Texas, Oklahoma, and Kansas have experienced increased rates of seismicity in recent years, providing new datasets of earthquake recordings to develop ground motion prediction models for this particular region of the Central and Eastern North America (CENA). This paper outlines a framework for using Artificial Neural Networks (ANNs) to develop
arxiv   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Compatible Ground Motion Models for South Korea Using Moderate Earthquakes

Applied Sciences
Due to a heightened interest in the field of earthquakes after two moderately sized earthquakes occurred in Gyeongju and Pohang, this study explores which ground motion prediction equations are compatible for the South Korea region.
Soo-jin Jung, Eric Yee
doaj   +1 more source

Effects of ground on earthquake motion [PDF]

Bulletin of the Seismological Society of America, 1957
ABSTRACT Earthquake damage at a given location depends on properties of the arriving elastic waves, of the ground at the shaken site, and of the structures involved. To investigate effects of the ground on the motion at the surface, five identical seismographs have been operated temporarily at 25 locations within 30 miles from the ...
openaire   +3 more sources

Regional differences in subduction ground motions [PDF]

, 2012
International ...
Beauval, Céline, Cotton, F., Abrahamson, N., Theodulidis, N., Delavaud, E., Rodriguez, L., Scherbaum, F., Haendel, A.   +7 more
openaire   +4 more sources