Results 51 to 60 of about 6,716,287 (298)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Impact of Multiple Faults on the Maximum Credible Ground-Motion Parameters of Large Earthquakes at a Near-Field Site

open access: yesApplied Sciences
The ground-motion simulation of regional-specific earthquake scenarios is crucial for the seismic design of key facilities. Herein, we considered parameter uncertainty in ground-motion simulations and the impact of multiple faults when determining the ...
Jiangyi Li, Zhengfang Li, Bengang Zhou
doaj   +1 more source

Support Vector Regression for the Relationships between Ground Motion Parameters and Macroseismic Intensity in the Sichuan–Yunnan Region

open access: yesApplied Sciences, 2020
In this paper, a nonlinear regression method called a support vector regression (SVR) is presented to establish the relationship between engineering ground motion parameters and macroseismic intensity (MSI).
Dongwang Tao   +5 more
doaj   +1 more source

Research on seismic ground motion parameters applicable to the safety of rectangular shallow tunnel

open access: yesAdvances in Mechanical Engineering, 2022
The objective of this paper is to optimize the selection of seismic ground motion intensity indexes in the seismic fortification of urban shallow-buried rectangular tunnels.
Dong An, Zheng Chen, Guangyao Cui
doaj   +1 more source

Generation of Site-Dependent Earthquake Ground Motion Parameters

open access: yesNepalese Journal of Engineering, 2005
The Kathmandu Valley, with many monumental and heritage structures, lies in a zone of high seismic risk. The neo-tectonic activities in the Himalayan region and the unconsolidated soil sediment are the major reasons for the high intensities of the ground motion in the valley.
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Pose Invariant Gait Analysis And Reconstruction [PDF]

open access: yes, 2005
One of the unique advantages of human gait is that it can be perceived from a distance. A varied range of research has been undertaken within the field of gait recognition.
Spencer, Nicholas M.
core   +1 more source

Feasibility of Applying Kriging for Earthquake Ground Motion Intensity Measures in South Korea

open access: yesApplied Sciences
Estimating ground motion parameters at an unsampled site is challenging for seismologists and engineers alike. An attempt is made to apply Kriging interpolation to estimate peak ground accelerations at specific nuclear power plant sites.
Eric Yee, Jung-ho Kim
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Applicability of Accurate Ground Motion Estimation Using Initial P Wave for Earthquake Early Warning

open access: yesFrontiers in Earth Science, 2021
The earthquake early warning (EEW) system is capable of mitigating seismic hazards and reducing deaths, injuries, and economic losses. Although EEW approaches have already been developed worldwide, improving the accuracy and applicability is still ...
Zijun Wang   +3 more
doaj   +1 more source

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