Results 61 to 70 of about 6,716,287 (298)

Statistical analysis of earthquake ground motion parameters [PDF]

open access: yes, 1979
Several earthquake ground response parameters that define the strength, duration, and frequency content of the motions are investigated using regression analyses techniques; these techniques incorporate statistical significance testing to establish the terms in the regression equations.
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Interpolation free subpixel accuracy motion estimation [PDF]

open access: yes, 2006
Licensed and exploited by ProVision Communications Technologies Ltd. Accurate motion estimation at sub pixel resolution is computationally complex. Method overcomes difficulties of subpixel search in real time implementation of H.264 codec, through ...
Hill, PR   +3 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Assessment of Seismic Intensity Measures on Liquefaction Response: A Case Study of Yinchuan Sandy Soil

open access: yesBuildings
The proliferation of tunnel and subway networks in urban areas has heightened concerns regarding their vulnerability to seismic-induced liquefaction.
Bowen Hu   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Prediction of High-Frequency Ground Motion Parameters Based on Weak Motion Data

open access: yes, 2012
This research was carried out using computational facilities procured through the European Regional Development Fund, Project ERDF-080 ‘A supercomputing laboratory for the University of Malta (http://www.um.edu.mt/research/scienceeng/erdf_080).
D'Amico, Sebastiano   +3 more
openaire   +3 more sources

Motion computation and visual orientation in flies [PDF]

open access: yes, 1993
Egelhaaf M, Borst A. Motion computation and visual orientation in flies. Comparative Biochemistry and Physiology, A: Comparative Physiology. 1993;104(4):659-673.Visual orientation greatly relies on the evaluation of the motion patterns received by the ...
Egelhaaf, M.   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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