Results 41 to 50 of about 5,461,852 (244)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Multi-moving-target imaging in a synthetic aperture radar (SAR) system poses a significant challenge owing to target defocusing and being contaminated by strong background clutter.
Chang Ding, Huilin Mu, Yun Zhang
doaj +1 more source
A Large Along-Track Baseline Approach for Ground Moving Target Indication Using TanDEM-X [PDF]
In the paper a new method for ground moving target indication (GMTI) using two satellites (i.e. the TerraSAR-X and the TanDEM-X satellite) together is presented.
Baumgartner, Stefan +2 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Moving Target Signals in High Resolution Wide Swath SAR [PDF]
In this paper the impact of two high resolution wide swath synthetic aperture radar imaging techniques, extraction of signals from azimuth subsampled spectra and subpulse azimuth beamsteering on transmit, on ground moving target signals is analyzed ...
Krieger, Gerhard, Gabele, Martina
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
In recent years, the detection performance of SAR-GMTI (synthetic aperture radar-ground moving target indication) algorithm based on deep learning has always been limited by insufficient measured data due to the heavy operation complexity and high cost ...
Hui Liu +5 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source

