Results 51 to 60 of about 5,182,060 (233)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Ground moving target indication with synthetic aperture radars for maritime surveillance

open access: yes, 2023
The explosive growth of shipping traffic all over the World, with around three quarters of the total trade goods and crude oil transported by sea, has raised newly emerging concerns (economical, ecological, social and geopolitical). Geo-information (location and speed) of ocean-going vessels is crucial in the maritime framework, playing a key role in ...
openaire   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Spatio-Temporal Matching of Moving Objects in Optical and SAR-Data [PDF]

open access: yes, 2007
We present an approach for spatio-temporal co-registration of dynamic objects in Synthetic Aperture Radar (SAR) and optical imagery. Goal of this work is the performance evaluation of vehicle detection and velocity estimation from SAR images when ...
Weihing, Diana   +3 more
core  

First Results Of TanDEM-X Along-Track Interferometry [PDF]

open access: yes, 2012
The interferometric imaging modes of the TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) satellite formation offer improved along-track interferometric capabilities e.g. through longer and multiple baselines.
Hartmut Runge   +3 more
core   +1 more source

Optimal circular flight of multiple UAVs for target tracking in urban areas [PDF]

open access: yes, 2009
This work is an extension of our previous result in which a novel single-target tracking algorithm for fixed-wing UAVs (Unmanned Air Vehicles) was proposed.
Kim, J., Kim, Y.
core   +5 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

First Spaceborne SAR-GMTI Experimental Results for the Chinese Gaofen-3 Dual-Channel SAR Sensor

open access: yesSensors, 2017
In spaceborne synthetic aperture radar (SAR) sensors, it is a challenging task to detect ground slow-moving targets against strong clutter background with limited spatial channels and restricted pulse repetition frequency (PRF).
Chenghao Wang   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ground moving target indication of polarimetric interferometric synthetic aperture radar using joint scattering vector

open access: yesIET Radar, Sonar & Navigation
Ground moving target indication (GMTI) plays a critical role in both civilian applications and military applications. The accuracy of complex images coregistration is a major factor for multichannel synthetic aperture radar (SAR) GMTI.
Jing Xu   +3 more
doaj   +1 more source

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