Results 61 to 70 of about 5,461,852 (244)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

SAR moving target imaging using group sparsity [PDF]

, 2013
SAR imaging of scenes containing moving targets results in defocusing in the reconstructed images if the SAR observation model used in imaging does not take the motion into account.
Önhon, Özben Naime, Çetin, Müjdat
core   +1 more source

Multi-Channel SAR System Design for HRWS and GMTI in Low PRF

IEEE Access, 2020
High-resolution and wide-swath (HRWS) is an important challenge in synthetic aperture radar (SAR). Combined SAR with array, the azimuth dual-channel SAR configuration achieves high azimuth resolution and HRWS in low Pulse repetition frequency (PRF) by ...
Xuepan Zhang, Chen Yang, Xuejing Zhang, Qingqing Lin   +3 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

A Novel Scattered Wave Deception Jamming Against Three Channel SAR GMTI

IEEE Access, 2018
Many jamming methods have been proposed against three-channel synthetic aperture radar (SAR) ground moving target indication based on the stationary jammer.
Chunxi Dong, Xin Chang
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Brief Analysis on the Development and Application of Multi-Input Multi-Output Synthetic Aperture Radar

Leida xuebao, 2014
Recently, a novel conception of Synthetic Aperture Radar (SAR) based on Multi-Input Multi-Output (MIMO) technology draws much attention for its potential advantages.
Zhou Wei, Liu Yong-xiang, Li Xiang, Ling Yong-shun   +3 more
doaj   +1 more source

High-resolution Wide-swath SAR Moving Target Imaging Technology Based on Distributed Compressed Sensing

Leida xuebao, 2020
High-resolution wide-swath SAR moving target imaging is of great significance for target tracking. To achieve target tracking, conversional space-based multichannel SAR technology requires a large number of channels.
PAN Jie, WANG Shuai, LI Daojing, LU Xiaochun   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source