Results 61 to 70 of about 1,486,491 (293)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Graphene-Substrate Effects on Characteristics of Weak-Coupling Bound Magnetopolaron

open access: yesAdvances in Condensed Matter Physics, 2020
Graphene has many unique properties which have made it a hotbed of scientific research in recent years. However, it is not expected intuitively that the strong effects of the substrate and Coulomb doping in the center of crystal cell on the polaron in ...
Zhao-Hua Ding   +4 more
doaj   +1 more source

Stripe-ordered superfluid and supersolid phases in attractive Hofstadter-Hubbard model

open access: yes, 2015
We use microscopic Bogoliubov-de Gennes formalism to explore the ground-state phase diagram of the single-band attractive Hofstadter-Hubbard model on a square lattice.
Iskin, M.
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Probabilistic Seismic Hazard Assessment for Taiwan

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2016
The Taiwan Earthquake Model (TEM) was established to assess the seismic hazard and risk for Taiwan by considering the social and economic impacts of various components from geology, seismology, and engineering.
Yu-Ju Wang   +6 more
doaj   +1 more source

Effects of sea-level rise on physiological ecology of populations of a ground-dwelling ant.

open access: yesPLoS ONE, 2020
INTRODUCTION:Sea-level rise is a consequence of climate change that can impact the ecological and physiological changes of coastal, ground-dwelling species.
L M Hooper-Bùi   +6 more
doaj   +1 more source

Strong interfacial exchange field in the graphene/EuS heterostructure

open access: yes, 2016
Exploiting 2D materials for spintronic applications can potentially realize next-generation devices featuring low-power consumption and quantum operation capability.
Cha, Wujoon   +11 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Time‐Domain Geoelectrical Modeling and Experimental Validation of Ground Potential Rise in Multilayer Soil Structures during Fault Events

open access: yesEnergy Science & Engineering
Accurate characterization of subsurface electrical behavior during high‐energy fault events is critical for both geotechnical safety assessment and the protection of power infrastructure.
Wulfran Fendzi Mbasso   +7 more
doaj   +1 more source

Ground Return Current Behaviour in High Voltage Alternating Current Insulated Cables

open access: yesEnergies, 2014
The knowledge of ground return current in fault occurrence plays a key role in the dimensioning of the earthing grid of substations and of cable sealing end compounds, in the computation of rise of earth potential at substation sites and in ...
Roberto Benato   +4 more
doaj   +1 more source

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