Results 141 to 150 of about 4,330,694 (342)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Existence of solutions to nonlinear fractional Schrodinger equations with singular potentials
Electronic Journal of Differential Equations, 2016 We study the eigenvalue problem $$ (-\Delta)^s u(x)+ V(x)u(x)-K(x)|u|^{p-2}u(x) =\lambda u(x) \quad \text{in } \mathbb{R}^N, $$ where $s\in(0,1)$, $N>2s ...
Qingxuan Wang, Dun Zhao, Kai Wang
doaj
The effect of ground-state spin on fission and quasi-fission anisotropies
, 2003 R. D. Butt
openalex +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Electronic Journal of Differential Equations, 2017 This article concerns the Klein-Gordon-Maxwell type system when the nonlinearity has a quasicritical growth at infinity, involving zero mass potential, that is, $V(x)\to 0$, as $|x|\to\infty$.
Elson Leal de Moura +2 more
doaj
Remote Sensing of the Thermodynamic State of the Atmospheric Boundary Layer by Ground-Based Microwave Radiometry [PDF]
, 2001 J. Güldner, D. Spänkuch
openalex +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Two-parameter partially correlated ground-state electron density of some light spherical atoms from Hartree-Fock theory with nonintegral nuclear charge [PDF]
, 2007 Nicolás A. Cordero +2 more
openalex +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source