Results 71 to 80 of about 4,316,417 (322)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A Fast Time Synchronization Method for Large Scale LEO Satellite Networks Based on A Bionic Algorithm

Photonics
A fast time synchronization method for large-scale LEO satellite networks based on a bionic algorithm is proposed. Because the inter-satellite links are continuously established and interrupted due to the relative motion of the satellites, the topology ...
Yue Xu, Tao Dong, Jie Yin, Ziyong Zhang, Zhihui Liu, Hao Jiang, Jing Wu   +6 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Multiple Positive Solutions to a Kirchhoff Type Problem Involving a Critical Nonlinearity in ℝ3

Advanced Nonlinear Studies, 2017
In this paper, we investigate a class of Kirchhoff type problems in ℝ3{\mathbb{R}^{3}} involving a critical nonlinearity, namely,
Zhong Xiao-Jing, Tang Chun-Lei
doaj   +1 more source

Using vegetation indices to identify high chlorophyll tree cover in floodplains for carbon sequestration [PDF]

E3S Web of Conferences
The dynamics of changes of Chlorophyll vegetation index (CVI) and Red-edge chlorophyll index (CIRE) for plant cover during the springsummer period on river floodplains has been studied. Landscape sections with high photosynthetic activity were identified
Poletaev Arseniy, Lisetskii Fedor
doaj   +1 more source

Ground State Baryons in U(12) Scheme

, 2005
The properties of ground-state baryons of light-quarks are investigated in U(12)-classification scheme of hadrons, recently proposed by us. In U(12), in addition to the ordinary 56 of SU(6)SF, the existence of the extra 56 with positive-parity and 70 ...
Burkhardt, Eidelman, Eidelman, Ishida, Ishida, Ishida, Ishida, Ishida, Ishida, Ishida, Ishida, Koniuk, Muneyuki Ishida, Rosner   +13 more
core   +3 more sources

Moving Toward the Ground State [PDF]

Cell Stem Cell, 2015
Transferring mouse ESCs to a media supplemented with Mek and Gsk3β inhibitors (2i) provokes marked transcriptional and epigenetic changes, embodying a shift toward ground-state pluripotency. In this issue of Cell Stem Cell, Kolodziejczyk et al. (2015) examine population structures of ESCs while Galonska et al.
Kumar, Ishan, Ivanova, Natalia
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source