Results 81 to 90 of about 4,316,417 (322)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Experiments towards quantum information with trapped Calcium ions

open access: yes, 2000
Ground state cooling and coherent manipulation of ions in an rf-(Paul) trap is the prerequisite for quantum information experiments with trapped ions. With resolved sideband cooling on the optical S1/2 - D5/2 quadrupole transition we have cooled one and ...
Barton, P.   +10 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Instability of standing waves for the inhomogeneous Gross-Pitaevskii equation

open access: yesAIMS Mathematics, 2020
In this paper, we consider the instability of standing waves for an inhomogeneous Gross-Pitaevskii equation \[ i\psi_t +\Delta \psi -a^2|x|^2\psi +|x|^{-b}|\psi|^{p}\psi=0. \] This equation arises in the description of nonlinear waves such as propagation
Yongbin Wang, Binhua Feng
doaj   +1 more source

Spectroscopy of neutron-unbound $^{27,28}$F

open access: yes, 2012
The ground state of $^{28}$F has been observed as an unbound resonance $2\underline{2}0$ keV above the ground state of $^{27}$F. Comparison of this result with USDA/USDB shell model predictions leads to the conclusion that the $^{28}$F ground state is ...
Ash, S.   +18 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Fast ground-state-to-ground-state separation of small ion crystals

open access: yesPhysical Review A
Rapid separation of linear crystals of trapped ions into different subsets is critical for realizing trapped ion quantum computing architectures where ions are rearranged in trap arrays to achieve all-to-all connectivity between qubits. We introduce a general theoretical framework that can be used to describe the separation of same-species and mixed ...
Tyler H. Guglielmo   +3 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Inhomogeneous NLS with partial harmonic confinement

open access: yesAIMS Mathematics
We investigate the inhomogeneous nonlinear Schrödinger equation with partial harmonic confinement. First, we present a global well-posedness result for small data in the intercritical regime.
Saleh Almuthaybiri, Tarek Saanouni
doaj   +1 more source

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