Results 81 to 90 of about 871 (212)

Hierarchical Collagen Nanofiber Gels Recapitulate a Physiologically Relevant Tumor Stromal Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
The collagen nanofiber (CNF) gel supports cancer cell culture, exhibiting cell morphology and cancer‐related protein expression similar to Matrigel. It offers a higher collagen concentration than commercial gels. Additionally, the CNF gel allows replication of the high elasticity of in vivo cancer tissue by controlling collagen fiber sizes, ranging ...
Naoko Sasaki   +4 more
wiley   +1 more source

The prediction of surface settlements due to tunnelling in soft ground

open access: yes, 2016
The investigation of various soil models for the prediction of surface settlement profiles due to the excavation of a single tunnel in soft ground is described in this thesis. Both analytical and numerical methods are used. Emphasis is placed on the establishment of the width of the predicted settlement trough.
Chow, L, Chow, L.
openaire   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei   +9 more
wiley   +1 more source

Measurement analysis of strata deformation caused by construction of quasi-rectangular shield

open access: yesScientific Reports
This paper is based on a large cross-section quasi-rectangular shield tunnel project on Zhengzhou Metro Line 8, where field excavation tests were conducted to study the ground deformation patterns induced by quasi-rectangular shield tunneling through in ...
Shi-ju Ma   +5 more
doaj   +1 more source

NUMERICAL INVESTIGATION INTO EFFECTS OF LONG FACEBOLTING ON THE PREVENTION OF GROUND SURFACE SETTLEMENT

open access: yesDoboku Gakkai Ronbunshuu C, 2006
山岳トンネルの補助工法である長尺鏡止めボルトは,切羽の安定対策のみならず,地表面沈下の抑制対策としても採用されているが,長尺鏡止めボルトによる地表面沈下の抑制機構について十分な考察が行われていないのが現状である.本論文では,土被りの小さいトンネルを対象に,三次元数値解析によって,長尺鏡止めボルトによる地表面沈下の抑制効果について検討した結果,砂質土系地山でその効果が大きく,長尺鏡止めボルトは,切羽前方だけでなく切羽から地表面に向かう領域にも応力を拘束し,地表面沈下を抑制する効果があることがわかった.
OHTSUKA, Isamu   +3 more
openaire   +2 more sources

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

open access: yesAdvanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi   +10 more
wiley   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

Theoretical Analysis of Surface Settlement During Parallel Construction of a Double-Track Tunnel with Small Spacing

open access: yesBuildings
The construction of urban subway tunnels typically induces soil settlement within a specific radius of the surrounding area. However, the accuracy of current methods for predicting ground deformation curves corresponding to the excavation of double-track
Yanao Liu   +5 more
doaj   +1 more source

Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman   +7 more
wiley   +1 more source

Maximum surface settlement induced by shallow tunneling in layered ground [PDF]

open access: yesNaukovyi Visnyk Natsionalnoho Hirnychoho Universytetu, 2020
A Boustila   +3 more
openaire   +1 more source

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