Results 61 to 70 of about 6,384,714 (292)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Model test and numerical simulation of a new prefabricated double-row piles retaining system in silty clay ground

open access: yesUnderground Space, 2023
This paper introduces a new prefabricated recyclable double-row piles retaining system for excavations in silty clay ground. Laboratory model test and numerical simulation are conducted to study the system behavior upon excavation.
Ruisong Wang   +8 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Field measurement of time-space distribution behaviors of environmental settlement of an ultra-deep excavation in Shanghai soft ground

open access: yesYantu gongcheng xuebao, 2023
Based on the extensive field observations, the environmental deformation characteristics of a 31.3 m-deep excavation in Shanghai soft ground are investigated.
LI Hang 1, 4, LI Zewen 1, LIAO Shaoming 1, 2, LI Zhiyi 3, ZHONG Huawei 3
doaj   +1 more source

PREDICTION FOR THE MAXIMUM SETTLEMENTS OF GROUND SURFACE BY OPEN CUT

open access: yesDoboku Gakkai Ronbunshu, 1986
The present paper is concerned with the prediction for the maximum settlements of ground surface adjacent to open cut. Using many field measurements, statistical analysis were made for the maximum settlement and the distance from wall where more than 2mm settlement occured.
openaire   +2 more sources

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Ground settlement in loading process.mp4

open access: yes, 2023
Video illustrates the ground settlement in a loading process.
Tao Liu (11275885)   +1 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

ESTIMATION OF TUNNELING INDUCED GROUND SETTLEMENT USING PRESSURE RELAXATION METHOD

open access: yes, 2017
The prediction of ground settlement caused by tunnelling is frequently estimated using a specified tunnel volume loss, and by applying a semi-empirical method involving the Gaussian equation, and relying on engineer's experiences.
Sams, Mathew, Shiau, Jim, Jim Shiau
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy