Results 51 to 60 of about 6,384,714 (292)

Calculation Method for Investigating the Behavior of Ground Surface Settlement of Underpass Buildings in TBM Double-Line Tunnels

, 2022
This study aims to investigate the behavior of ground surface settlement in TBM double-line tunnels constructed under existing buildings and to devise a calculative representation for that behavior.
Yang Tang, Seisuke Okubo, Ting Ren, Hailong Zhang, Yuancheng Guo, Qinglin Li   +5 more
core   +1 more source

Evaluating the effect of EPBM operational parameters on surface settlement in soft ground [PDF]

Journal of Geophysics and Engineering, 2020
Abstract The present study investigates the effects of some essential earth pressure balance machine (EPBM) operational parameters, including face, annulus and grout pressures, on ground surface settlement during tunnel excavation. A numerical soil-tunnel-fluid coupled model was developed using the finite difference method (FDM) in ...
Ali Naghi Dehghan, Ehsan Bagheri, Meysam Khodaei, Rouzbeh Imani Kalehsar   +3 more
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Report: Jewish Agency Settlement Department, The Industrial Village, July 1974

, 1974
Textual: Report; staple holes, 11" x 8.5" (29.7 cm x 21.6 cm)Report from the Jewish Agency Settlement Department entitled "The Industrial Village: A New Form of Settlement… A New Form of Opportunity for Aliyah" from 1974. This report discusses a new form
Jewish Agency Settlement Department
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Calculation Method of Ground Settlement Caused by Mechanical Construction in Metro-Connected Aisle

Buildings
Mechanical construction of metro-connected aisles is a novel construction method in the field of metro engineering, and it is being gradually applied to practical projects at present.
Yueqiang Duan, Maolei Wang, Jinghe Wang, Yuxiang Guo, Fa Chang, Boyuan Zhang, Weiyu Sun   +6 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Analysis of the Additional Stress and Ground Settlement Induced by the Construction of Double-O-Tube Shield Tunnels in Sandy Soils

Applied Sciences, 2019
Double-O-tube shield tunneling has attracted increasing attention because it offers cost-efficiency in underground construction. Prediction of ground surface settlement and the variety of additional stresses induced by shield construction is crucial to ...
Wen Zhao, Peng-jiao Jia, Lin Zhu, Cheng Cheng, Jianyong Han, Yang Chen, Zhi-guo Wang   +6 more
doaj   +1 more source

Surface settlement prediction for EPB shield tunneling in sandy ground

KSCE Journal of Civil Engineering, 2017
Ground volume loss induced by shield tunnel construction is the major factor leading to ground settlement and deformation. The general equations predicting surface settlement based on ground volume loss involve a settlement trough width coefficient (parameter i) which in previous models was set as a constant in both the transverse and longitudinal ...
Yong Fang, Chuan He, Ali Nazem, Zhigang Yao, Jacob Grasmick   +4 more
openaire   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source