Results 51 to 60 of about 871 (212)

Sensitivity analysis of ground settlement induced by pipe-jacking construction in soft soil stratum [PDF]

E3S Web of Conferences, 2019
Taking the ground settlement while pipe-jacking construction in soft soil as the engineering background, the effect of pipe jacking were studied by numerical simulation.
Han Xianmin, Li Wenjiang, Chen Tao, Liu Wang   +3 more
doaj   +1 more source

Analysis of Settlement Behaviour of Soft Ground Under Wide Embankment

The Baltic Journal of Road and Bridge Engineering, 2021
An elastoplastic numerical model for calculating the consolidation settlement of wide embankment on soft ground is established using PLAXIS finite element software to investigate the settlement behaviour of soft ground under the wide embankment.
Xin Jiang, Xiaoli Chen, Yongguo Fu, Hanyan Gu, Jinming Hu, Xing Qiu, Yanjun Qiu   +6 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Effect of Lubricant Young’s Modulus on Surface Settlement Control During Pipe-Roof Construction Using Pipe-Jacking Method

Applied Sciences
During pipe-roof construction using pipe-jacking technology, lubricants are injected into the tail void to reduce pipe–soil friction and minimize soil loss. However, research on ground settlement caused by multiple adjacent pipe jackings remains limited,
Shuai Zhang, Takashi Sasaoka, Akihiro Hamanaka, Xiaohu Hu, Peng Ma, Hideki Shimada   +5 more
doaj   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Prediction of ground surface settlements by analytical and finite element methods

IOP Conference Series: Earth and Environmental Science
Abstract The soil surrounding the excavation of shallow tunnels may experience destructive deformation near the tunnels. Particularly in densely populated areas where land resources are scarce, ground subsidence caused by tunnel excavation, which in turn affects surrounding structures, deserves more attention.
Y H Wang, C C Lam, M H Lok
openaire   +1 more source

Microstructure Reconstruction in Battery Electrodes Using Machine Learning Based on Low‐Voltage Focused Ion Beam–Scanning Electron Microscopy Tomography Images

Advanced Engineering Materials, EarlyView.
Low‐voltage FIB‐SEM tomography combined with a image preprocessing pipeline improves phase contrast and enables reliable machine‐learning segmentation of conductive networks in lithium‐ion battery electrodes. Structural descriptors are extracted from segmented images, done semimanually and automated, and compared.
Lisa Beran, Vincent Nebel, Dominik Perius, Kshitij Kumar, Yannis Heim, Laura Bies, Tobias Kraus   +6 more
wiley   +1 more source