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The low frequency of circulating antigen-specific memory B cells is a considerable obstacle in the discovery and development of human monoclonal antibodies for therapeutic application.
Cheri L. Lamb +7 more
doaj +2 more sources
Antigen-Specific versus Non-Antigen-Specific Immunoadsorption in ABO-Incompatible Renal Transplantation. [PDF]
ABO-incompatible (ABOi) renal transplantation (RTx) from living donors is an established procedure to expand the donor pool for patients with end stage renal disease.
Gerold Thölking +8 more
doaj +1 more source
Immunogenetic status and breeding value of Holstein cows [PDF]
In the genealogical structure of the breeding stock, the highest specific weight is occupied by the Reflection Sovering and Vis bek Aydiala lines, accounting for 56.8 and 39.9% of animals, respectively.
Kaishev Vladimir +4 more
doaj +1 more source
The national-wide incidence of prostate-specific antigen testing trend for a decade in Korea by age group [PDF]
Purpose: To document nationwide serum prostate-specific antigen (PSA) testing trends over the past decade and to investigate the impact of testing on prostate cancer (PCa) detection.
Young Hwii Ko +2 more
doaj +1 more source
In Situ Peptide-MHC-II Tetramer Staining of Antigen-Specific CD4+ T Cells in Tissues. [PDF]
The invention of peptide-MHC-tetramer technology to label antigen-specific T cells has led to an enhanced understanding of T lymphocyte biology. Here we describe the development of an in situ pMHC-II tetramer staining method to visualize antigen-specific
Thamotharampillai Dileepan +3 more
doaj +1 more source
Patients with hematological malignancies are prioritized for COVID-19 vaccine due to their high risk for severe SARS-CoV-2 infection-related disease and mortality.
Susana Patricia Amaya Hernandez +9 more
doaj +1 more source
Specific delivery to antigen presenting cells (APC) and precise control of the intracellular fate of antigens are crucial to induce cellular immunity that directly and specifically attacks cancer cells.
Eiji Yuba +4 more
doaj +1 more source
Linkage group selection: towards identifying genes controlling strain specific protective immunity in malaria. [PDF]
Protective immunity against blood infections of malaria is partly specific to the genotype, or strain, of the parasites. The target antigens of Strain Specific Protective Immunity are expected, therefore, to be antigenically and genetically distinct in ...
Sittiporn Pattaradilokrat +2 more
doaj +1 more source
Helicobacter pylori (H. pylori) is a gram-negative pathogen classified as a class I carcinogen. The H. pylori urease B subunit (UreB) and heat shock protein A (HspA) are two important vaccine candidate antigens.
Xin Zhang +6 more
doaj +1 more source
We established a specific genotyping assay for HLA-A*01, which is one of the most frequently found HLA-A alleles in the Caucasian population. This assay uses the polymerase chain reaction (PCR) with allele group-specific primers (ASP).
Ikuma Kasuga +2 more
doaj +1 more source

