Cefuroxime axetil dosing regimens and probability of target attainment in adults and children
Aims Cefuroxime axetil exists in several dosage forms for oral administration, and is indicated for treatment of respiratory, genitourinary, skin and soft tissue infections. Evolving patterns of bacterial susceptibility, expressed as increasing minimum inhibitory concentrations (MICs), warrant monitoring of antibiotic efficacy.
Sven C. van Dijkman+3 more
wiley +1 more source
Optimized Machine Learning for Autonomous Enzymatic Reaction Intensification in a Self‐Driving Lab
A machine learning‐powered self‐driving lab accelerates enzymatic reaction optimization by autonomously navigating complex parameter spaces. Through over 10,000 simulated campaigns, we identified an optimal algorithm for efficient, automated optimization.
Sebastian Putz+5 more
wiley +1 more source
Group A Streptococcus among American Indian Persons, White Mountain Apache Tribal Lands, United States, 2016-2019<sup>1</sup>. [PDF]
Sutcliffe CG+8 more
europepmc +1 more source
Restoration of human tooth enamel
Human tooth enamel has remarkable properties but lacks self‐repair ability. Existing restorative materials cannot fully replicate enamel's microstructure and function, resulting in low restorative efficiency. This review summarizes the formation process and characteristics of enamel, and current restorative materials and future research directions are ...
Hanlin Liu+10 more
wiley +1 more source
Invasive group A streptococcus infections in the intensive care unit: an unsupervised cluster analysis of a multicentric retrospective cohort. [PDF]
Urbina T+20 more
europepmc +1 more source
Continuous purification of a parvovirus using two aqueous two‐phase extraction steps
Abstract Aqueous two‐phase systems (ATPS) are a liquid–liquid extraction method that offers low‐cost, continuous‐adaptable virus purification. A two‐step ATPS using polyethylene glycol (PEG) and sodium citrate that recovered 66% of infectious porcine parvovirus with 2.0 logs of protein removal and 1.0 logs of DNA removal in batch has now been run ...
Natalie M. Nold+11 more
wiley +1 more source
Group A Streptococcus Bacteraemia Presenting as Acute Limb Ischaemia in a Neonate: A Case Report. [PDF]
Muzaffar MM, Samani S, Van Der Velde P.
europepmc +1 more source
Persistent Group B streptococcus bacteremia without clinical “sepsis” in infants
Kenneth B. Roberts
openalex +1 more source