Results 101 to 110 of about 1,951,358 (319)

Group structured reasoning for coalescing group decisions

open access: yes, 2009
In this paper we present the notion of structured reasoning through a model, called the Generic/Actual Argument Model (GAAM). The model which has been used as a computational representation for machine modelling of reasoning and for hybrid combinations ...
Stranieri, Andrew, Yearwood, John
core   +1 more source

A decision support approach for group decision making under risk and uncertainty [PDF]

open access: yes, 2010
Cost-benefit analysis has long been used in decision making about public health and security. Frequently, risk and uncertainty are involved, and benefit and cost are not evenly shared by all stakeholders in the activities where public welfare is ...
Kendall, Graham   +11 more
core   +1 more source

Time to move? Factors associated with burden of care among informal caregivers of cognitively impaired older people facing housing decisions: secondary analysis of a cluster randomized trial

open access: yesBMC Geriatrics, 2019
Background Making health-related decisions about loved ones with cognitive impairment may contribute to caregiver burden of care. We sought to explore factors associated with burden of care among informal caregivers who had made housing decisions on ...
Alexandrine Boucher   +9 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Group Decision Making Under Risk: An Experiment with Student Couples [PDF]

open access: yes
In an experiment, we study risk-taking of cohabitating student couples, finding that couples’ decisions are closer to risk-neutrality than single partners’ decisions.
Haoran He   +2 more
core  

Beyond group-level explanations for the failure of groups to solve hidden profiles: The individual preference effect revisited [PDF]

open access: yes, 2010
The individual preference effect supplements the predominant group-level explanations for the failure of groups to solve hidden profiles. Even in the absence of dysfunctional group-level processes, group members tend to stick to their suboptimal initial ...
Rudolf Kerschreiter   +12 more
core   +1 more source

Enhancing resource allocation in drought mitigation through a group multicriteria sorting model: a case study of Rio Grande do Norte, Brazil

open access: yesWater Policy
Drought is a natural phenomenon that poses a significant threat to water resources in affected regions. The detrimental effects of this extreme weather event, regardless of its type, have had an impact, necessitating concrete resource allocation projects
Gabriel de Oliveira Castro   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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