Results 121 to 130 of about 94,048 (263)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Association between shift work and insomnia in nurses: a cross-sectional study using the Athens Insomnia Scale. [PDF]
Front Public HealthSzczupak M, Kobak J, Krupa-Nurcek S.
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Improving Resident Doctors' Preparedness for General Medical On-Call Shifts Through Structured Induction Resources: A Quality Improvement Project at a Large UK Teaching Hospital. [PDF]
CureusBrighton C, Anderson B.
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Prepare medical graduates for residency through near-peer teaching: addressing reciprocal determinants. [PDF]
Ann MedChien L +11 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Metabolic Syndrome, Cardiovascular Risk, and Health-Related Quality of Life Among Police Officers in Madeira: A Cross-Sectional Occupational Health Study. [PDF]
Healthcare (Basel)Pina J, Santos V, Massuça LM.
europepmc +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Voices from the classroom: Teachers' perspectives on collaboration with speech-language therapists in learners with special educational needs schools. [PDF]
S Afr J Commun DisordMahomed Joosub H, De Jongh M, Mothapo R.
europepmc +1 more source