Results 61 to 70 of about 94,048 (263)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source

Settling a conflict of interest in judicial and lawyer activity: general and specific issues (by the example of class proceedings)

Russian Journal of Economics and Law
Objective: to clarify the concept of “conflict of interest”, to identify the peculiarities of conflict of interest resolution in group proceedings, and to develop practical recommendations to prevent conflict of interest in judicial and advocacy ...
O. S. Belosludtsev, I. V. Ginzburg
doaj   +1 more source

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen, Ronald D. Barr, Erin Strumpf, Mariam El‐Zein, Eduardo L. Franco, Talía Malagón   +5 more
wiley   +1 more source

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman, Maria Yasmine, Dunia Hatabah, Noor Alzraikat, Frank Harris, Lou Ann Brown, Satheesh Chonat, Nitya Bakshi, Chris A. Rees, Carlton Dampier, Claudia R. Morris   +10 more
wiley   +1 more source

DNA sequencing in oncology: a focus group study on a duty to recontact

Future Science OA
Particularly in genetics, former results can gain new meaning in the course of time. This raises questions about when professionals should recontact patients with new information. The aim of this focus group study is to clarify how different stakeholders in oncology think about the extent and limits of a duty to recontact.One focus group with oncology ...
Noor A.A. Giesbertz, Lars S. Assen, Wim H. van Harten, Annelien L. Bredenoord   +3 more
openaire   +6 more sources

Fast Group Communication Scheduling in Duty-Cycled Multihop Wireless Sensor Networks [PDF]

, 2012
We study group communication scheduling in duty-cycled multi-hop wireless sensor networks. Assume that time is divided into time-slots and we group multiple consecutive time-slots into periods. Each node can transmit data at any time-slot while it only wakes up at its active time-slot of every period and thus be allowed to receive data.
XiaoHua Xu 0002, Jiannong Cao 0001, Peng-Jun Wan   +2 more
openaire   +1 more source

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu, Masaharu Akiyama, Toshikazu Itabashi, Jun Hayakawa, Takahiro Kikuchi, Ryohei Fukunaga, Katsuyoshi Koh, Takahiro Ueda   +7 more
wiley   +1 more source

The Effect of Mindfulness on the Family Well-Being in Mother who Works as a Nurse

IJNP (Indonesian Journal of Nursing Practices), 2019
Background: Mothers who work as nurses are one of the vulnerable groups and are at risk of imbalance of roles in work and family due to multiple roles. The dual role requires working mothers to carry out their duties as mothers and wives at home, while ...
Arni Nur Rahmawati, Meidiana Dwidiyanti, Muhammad Mu'in   +2 more
doaj   +1 more source

The Duty to Promote Digital Minimalism in Group Agents

AbstractIn this chapter, we turn our attention to the effects of the attention economy on our ability to act autonomously as a group. We begin by clarifying which sorts of groups we are concerned with, which are structured groups (groups sufficiently organized that it makes sense to attribute agency to the group itself).
Timothy Aylsworth, Clinton Castro
openaire   +1 more source